Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 4/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | TUBB4A | P04350 | 4/20 | 0.45 |
| ▸ | TUBB | P07437 | 4/20 | 0.45 |
| ▸ | TUBA3C | P0DPH7 | 4/20 | 0.45 |
| ▸ | TUBA1B | P68363 | 4/20 | 0.45 |
| ▸ | TUBA4A | P68366 | 4/20 | 0.45 |
| ▸ | TUBB4B | P68371 | 4/20 | 0.45 |
| ▸ | TUBB3 | Q13509 | 4/20 | 0.45 |
| ▸ | TUBB2A | Q13885 | 4/20 | 0.45 |
| ▸ | TUBB8 | Q3ZCM7 | 4/20 | 0.45 |
| ▸ | TUBA3E | Q6PEY2 | 4/20 | 0.45 |
| ▸ | TUBA1A | Q71U36 | 4/20 | 0.45 |
| ▸ | TUBA1C | Q9BQE3 | 4/20 | 0.45 |
| ▸ | TUBB6 | Q9BUF5 | 4/20 | 0.45 |
| ▸ | TUBB2B | Q9BVA1 | 4/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7741712 | 0.76 | MTNR1A (0.60) | MTNR1AALDH1A1GAAHPGDNPC1 | |
| Hydrochloric Acid SCHEMBL5424364 | 0.75 | MTNR1A (0.50) | MTNR1AALDH1A1GAAHPGDNPC1 | |
| SCHEMBL4508144 | 0.74 | CYP4F2 (0.49) | MTNR1AALDH1A1GAAHPGDNPC1 | |
| SCHEMBL11418268 | 0.73 | MTNR1A (0.58) | MTNR1AALDH1A1MTNR1BCYP4F2CYP4A11 | |
| SCHEMBL8711145 | 0.73 | ALOX5 (0.45) | ALDH1A1GAAHPGDNPC1RAB9A | |
| SCHEMBL19763065 | 0.72 | ALDH1A1 (0.61) | ALDH1A1HPGDNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL8291691 | 0.72 | MTNR1A (0.64) | MTNR1AALDH1A1MTNR1B | |
| SCHEMBL8292283 | 0.72 | CYP2D6 (0.68) | MTNR1AALDH1A1HPGDRAB9ASMN1; SMN2 | |
| SCHEMBL9671446 | 0.72 | CYP4F2 (0.47) | MTNR1AALDH1A1GAAHPGDNPC1 | |
| SCHEMBL11082347 | 0.72 | CYP4F2 (0.47) | MTNR1AALDH1A1GAAHPGDNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5945561-A | ANTIINFLAMMATORY AGENT, RHEUMATIC DISORDERS, SKIN DISORDERS,ANTISCARRING AGENT | BRISTOL-MYERS SQUIBB COMPANY (US) | 1999-08-31 | — | — | US | disclosed |
| WO-1998049136-A1 | RETINOID-LIKE COMPOUNDS | BRISTOL-MYERS SQUIBB COMPANY (US) | 1998-11-05 | — | — | WO | disclosed |