Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Sulfuric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.35 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.35 |
| ▸ | SLC22A3 | O75751 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.32 |
| ▸ | NNMT | P40261 | 1/20 | 0.31 |
| ▸ | CHAT | P28329 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Sulfuric Acid SCHEMBL1745559 | 0.97 | USP2 (0.37) | USP2SLC22A2SLC22A1SLC22A3SLC6A4 | |
| SCHEMBL1005223 | 0.89 | USP2 (0.35) | USP2SLC22A2SLC22A1SLC22A3SLC6A4 | |
| Sulfuric Acid SCHEMBL1745561 | 0.86 | MEN1 (0.40) | USP2SLC22A2SLC22A1SLC22A3SLC6A4 | |
| SCHEMBL398916 | 0.82 | RAD52 (0.37) | USP2SLC22A2SLC22A1SLC22A3SLC6A4 | |
| Trifluoromethanesulfonic Acid SCHEMBL321089 | 0.80 | KCNH2 (0.40) | — | |
| Sulfuric Acid SCHEMBL1745560 | 0.80 | HDAC8 (0.39) | USP2SLC22A2SLC22A1SLC22A3SLC6A4 | |
| Trifluoromethanesulfonic Acid SCHEMBL8493995 | 0.79 | KCNH2 (0.39) | — | |
| Phosphine SCHEMBL28449233 | 0.78 | — | — | |
| SCHEMBL9040376 | 0.78 | SLC22A2 (0.47) | SLC22A2SLC22A1SLC22A3SLC6A4HDAC8 | |
| SCHEMBL27002 | 0.78 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6420616-B1 | NITRATING NAPHTHALENE WITH NITRIC ACID | BAYER AKTIENGESELLSCHAFT (DE) | 2002-07-16 | — | — | US | claimed |
| US-6420616-B1 | NITRATING NAPHTHALENE WITH NITRIC ACID | BAYER AKTIENGESELLSCHAFT (DE) | 2002-07-16 | — | — | US | disclosed |