Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Sulfuric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC8 | Q9BY41 | 5/20 | 0.39 |
| ▸ | NNMT | P40261 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.36 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.36 |
| ▸ | SLC22A3 | O75751 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | CA5A | P35218 | 1/20 | 0.35 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.35 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.33 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.33 |
| ▸ | CHAT | P28329 | 2/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | BCHE | P06276 | 3/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | GLA | P06280 | 2/20 | 0.31 |
| ▸ | ACHE | P22303 | 2/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | FDPS | P14324 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1568886 | 0.92 | HDAC8 (0.37) | HDAC8NNMTUSP2SLC22A2SLC22A1 | |
| Sulfuric Acid SCHEMBL1745561 | 0.89 | MEN1 (0.40) | HDAC8NNMTUSP2SLC22A2SLC22A1 | |
| SCHEMBL398917 | 0.85 | HDAC8 (0.33) | HDAC8NNMTUSP2SLC22A2SLC22A1 | |
| SCHEMBL9040376 | 0.80 | SLC22A2 (0.47) | HDAC8SLC22A2SLC22A1SLC22A3SLC6A4 | |
| SCHEMBL27002 | 0.80 | — | — | |
| Sulfuric Acid SCHEMBL7741793 | 0.80 | USP2 (0.35) | HDAC8NNMTUSP2SLC22A2SLC22A1 | |
| Oxalic Acid SCHEMBL21814395 | 0.79 | NNMT (0.38) | HDAC8NNMTUSP2SLC22A2SLC22A1 | |
| Hydroxyamine SCHEMBL4938065 | 0.78 | — | — | |
| Formaldehyde SCHEMBL28095212 | 0.78 | SLC22A2 (0.41) | HDAC8NNMTUSP2SLC22A2SLC22A1 | |
| SCHEMBL3881682 | 0.78 | LMNA (0.36) | USP2SLC6A4LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114787298-B | Two-component (2K) curable adhesive composition | 汉高股份有限及两合公司 | 2023-10-31 | — | — | CN | disclosed |
| CN-105646339-A | Method for preparing nicotinic acid by low-temperature reaction crystallization | 西安航天华威化工生物工程有限公司 | 2016-06-08 | — | — | CN | disclosed |
| EP-2467026-B1 | HEALTHY COFFEE AND METHODS OF ITS PRODUCTION | TCHIBO GMBH (DE) | 2013-10-23 | — | — | EP | disclosed |
| US-8524307-B2 | Healthy coffee and methods of its production | TCHIBO GMBH (DE) | 2013-09-03 | — | — | US | disclosed |
| US-20130156928-A1 | HEALTHY COFFEE AND METHODS OF ITS PRODUCTION | TCHIBO GMBH (DE) | 2013-06-20 | — | — | US | disclosed |
| EP-2467026-A1 | HEALTHY COFFEE AND METHODS OF ITS PRODUCTION | Tchibo GmbH (DE) | 2012-06-27 | — | — | EP | disclosed |
| WO-2011134656-A1 | HEALTHY COFFEE AND METHODS OF ITS PRODUCTION | TCHIBO GMBH (DE) | 2011-11-03 | — | — | WO | disclosed |
| EP-2382868-A1 | Healthy coffee and method of its production | Tchibo GmbH (DE) | 2011-11-02 | — | — | EP | disclosed |
| US-4258194-A | Process for producing 2,3,5-trichloropyridine | CIBA-GEIGY CORPORATION (US) | 1981-03-24 | — | — | US | disclosed |
| US-4176020-A | Process for electrolytic dimerization of N-substituted pyridinium salt | ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) | 1979-11-27 | — | — | US | disclosed |