Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCC9 | O60706 | 12/20 | 0.56 |
| ▸ | KCNJ11 | Q14654 | 12/20 | 0.56 |
| ▸ | ABCC8 | Q09428 | 8/20 | 0.56 |
| ▸ | KCNJ8 | Q15842 | 8/20 | 0.56 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.55 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.55 |
| ▸ | NAMPT | P43490 | 3/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7741529 | 0.91 | ABCC9 (0.58) | ABCC9KCNJ11ABCC8KCNJ8CYP11B1 | |
| SCHEMBL4682843 | 0.88 | CYP11B1 (0.59) | ABCC9KCNJ11ABCC8KCNJ8CYP11B1 | |
| SCHEMBL4682845 | 0.88 | CYP11B1 (0.59) | ABCC9KCNJ11ABCC8KCNJ8CYP11B1 | |
| SCHEMBL6611583 | 0.87 | ABCC9 (0.54) | ABCC9KCNJ11ABCC8KCNJ8CYP11B1 | |
| SCHEMBL6694111 | 0.87 | KCNJ11 (0.56) | ABCC9KCNJ11ABCC8KCNJ8CYP11B1 | |
| SCHEMBL6647532 | 0.86 | ABCC9 (0.54) | ABCC9KCNJ11ABCC8KCNJ8CYP11B1 | |
| SCHEMBL7742284 | 0.86 | ABCC9 (0.54) | ABCC9KCNJ11ABCC8KCNJ8CYP11B1 | |
| SCHEMBL6615293 | 0.86 | CYP11B1 (0.57) | ABCC9KCNJ11ABCC8KCNJ8CYP11B1 | |
| SCHEMBL6613703 | 0.85 | KCNQ3 (0.54) | KCNJ11 | |
| SCHEMBL6643601 | 0.85 | KCNJ11 (0.58) | ABCC9KCNJ11ABCC8KCNJ8KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1198456-A2 | POTASSIUM CHANNEL OPENERS | Abbott Laboratories (US) | 2002-04-24 | — | — | EP | disclosed |
| WO-2001009096-A2 | POTASSIUM CHANNEL OPENERS | ABBOTT LABORATORIES (US) | 2001-02-08 | — | — | WO | disclosed |