SCHEMBL7742563

SCHEMBL7742563

O=P(O)(O)C(Cc1ccccc1)Cc1ccccc1

nearest known ligand 0.64

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
LAP3 P28838 5/20 0.64
ANPEP P15144 5/20 0.64
ACP3 P15309 5/20 0.62
SRC P12931 1/20 0.52
ERAP1 Q9NZ08 2/20 0.50
ERAP2 Q6P179 2/20 0.50
CYP1A2 P05177 1/20 0.50
ALPI P09923 1/20 0.47
PKM P14618 1/20 0.47
PTGS1 P23219 1/20 0.47
XIAP P98170 1/20 0.47
SLC7A5 Q01650 1/20 0.47
TSHR P16473 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2224720 0.86 LAP3 (0.55) LAP3ANPEPACP3SRCCYP1A2
SCHEMBL7158870 0.82 LAP3 (0.64) LAP3ANPEPACP3ERAP1ERAP2
SCHEMBL27481841 0.80 LAP3 (0.62) LAP3ANPEPACP3ERAP1ERAP2
SCHEMBL10714585 0.80 LAP3 (0.62) LAP3ANPEPACP3ERAP1ERAP2
SCHEMBL16057402 0.79 LAP3 (0.47) LAP3ANPEPACP3ERAP2CYP1A2
SCHEMBL2375608 0.78 LAP3 (1.00) LAP3ANPEPACP3ERAP1ERAP2
SCHEMBL8740148 0.78 LAP3 (1.00) LAP3ANPEPACP3ERAP1ERAP2
SCHEMBL8341042 0.78 LAP3 (0.60) LAP3ANPEPACP3ERAP1ERAP2
SCHEMBL10710542 0.78 LAP3 (0.60) LAP3ANPEPACP3ERAP1ERAP2
SCHEMBL31343657 0.78 LAP3 (0.60) LAP3ANPEPACP3ERAP1ERAP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0759976-A4 THE ISOLATION AND PRODUCTION OF CATALYTIC ANTIBODIES USING PHAGE TECHNOLOGY IGEN INT INC (US) 2001-02-07 EP disclosed
US-5855885-A FROM BACTERIOPHAGE; CLONING, SCREENING WELLSTAT BIOCATALYSIS, LLC 1999-01-05 US disclosed
EP-0759976-A1 THE ISOLATION AND PRODUCTION OF CATALYTIC ANTIBODIES USING PHAGE TECHNOLOGY IGEN, INC. (US) 1997-03-05 EP disclosed
WO-1996000733-A1 DIPHOSPHATE OR TRIPHOSPHATE NON-HYDROLYSABLE STABLE ANALOGUES AND METHODS FOR THEIR PREPARATION CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) 1996-01-11 WO disclosed
WO-1995027045-A1 THE ISOLATION AND PRODUCTION OF CATALYTIC ANTIBODIES USING PHAGE TECHNOLOGY IGEN, INC. (US) 1995-10-12 WO disclosed