Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 6/20 | 0.37 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.34 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.34 |
| ▸ | NAAA | Q02083 | 1/20 | 0.33 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.32 |
| ▸ | LPAR5 | Q9H1C0 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MMP1 | P03956 | 1/20 | 0.31 |
| ▸ | MMP13 | P45452 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8542626 | 0.87 | RAB9A (0.33) | HIF1AMEN1ALDH1A1KMT2AKDM4E | |
| SCHEMBL7463037 | 0.85 | SMN1; SMN2 (0.38) | HIF1ASERPINE1MEN1KMT2AKDM4E | |
| SCHEMBL7469946 | 0.84 | ALDH1A1 (0.35) | CHEK2ALDH1A1CYP1A2CYP2D6CYP2C19 | |
| SCHEMBL8030793 | 0.84 | HIF1A (0.35) | HIF1AMEN1ALDH1A1CYP1A2CYP2D6 | |
| SCHEMBL7467262 | 0.82 | MAPK14 (0.39) | HIF1ACHEK2KMT2A | |
| SCHEMBL7469591 | 0.81 | RAB9A (0.31) | ALDH1A1KDM4ESMN1; SMN2TDP1L3MBTL1 | |
| SCHEMBL7742899 | 0.80 | HIF1A (0.45) | HIF1ASERPINE1 | |
| SCHEMBL7742903 | 0.80 | HIF1A (0.45) | HIF1ASERPINE1 | |
| SCHEMBL8725195 | 0.80 | HIF1A (0.32) | HIF1A | |
| SCHEMBL7470568 | 0.79 | MAPK14 (0.38) | HIF1AMEN1KMT2AKDM4ESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6420423-B1 | PESTICIDE FOR USE ON CEREALS, BEETS, FRUITS, BERRIES, AND BEANS; KILLS MITES, INSECTS, TERMITES, LICE, FLEAS, AND FUNGUS; TOLERATED WELL BE ANIMALS, PLANTS, AND FISH | BAYER AKTIENGESELLSCHAFT (DE) | 2002-07-16 | — | — | US | disclosed |
| EP-0865424-A1 | PESTICIDES | Novartis AG (CH) | 1998-09-23 | — | — | EP | disclosed |
| WO-1997020809-A1 | PESTICIDES | NOVARTIS AG (CH) | 1997-06-12 | — | — | WO | disclosed |