Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 7/20 | 0.60 |
| ▸ | F2 | P00734 | 4/20 | 0.60 |
| ▸ | PLAU | P00749 | 3/20 | 0.57 |
| ▸ | PLG | P00747 | 4/20 | 0.57 |
| ▸ | ST14 | Q9Y5Y6 | 2/20 | 0.57 |
| ▸ | HPN | P05981 | 1/20 | 0.57 |
| ▸ | HGFAC | Q04756 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8654566 | 0.93 | F2 (0.59) | F10F2PLAUPLGST14 | |
| SCHEMBL8654561 | 0.93 | F2 (0.59) | F10F2PLAUPLGST14 | |
| SCHEMBL9074163 | 0.90 | F2 (0.65) | F10F2 | |
| SCHEMBL9710642 | 0.88 | F2 (0.69) | F10F2PLAUPLGST14 | |
| SCHEMBL8955035 | 0.87 | F2 (0.62) | F10F2PLAUPLGST14 | |
| SCHEMBL8954841 | 0.87 | F10 (0.59) | F10F2PLAUPLGST14 | |
| SCHEMBL7350464 | 0.86 | F2 (0.59) | F10F2PLAUPLGST14 | |
| SCHEMBL6971395 | 0.86 | F2 (0.59) | F10F2PLAUPLGST14 | |
| SCHEMBL9710394 | 0.86 | F2 (0.68) | F10F2PLAUPLGST14 | |
| SCHEMBL8954726 | 0.86 | F10 (0.75) | F10F2PLAUPLGST14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0820453-A4 | THROMBIN INHIBITORS | MERCK & CO INC (US) | 2001-08-29 | — | — | EP | disclosed |
| EP-0820453-A1 | THROMBIN INHIBITORS | Merck & Co., Inc. (US) | 1998-01-28 | — | — | EP | disclosed |