Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | GRIN2B | Q13224 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.37 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.37 |
| ▸ | MGAM | O43451 | 2/20 | 0.36 |
| ▸ | SI | P14410 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4986264 | 0.87 | KMT2A (0.38) | KMT2ACYP2D6KDM4EOPRM1OPRD1 | |
| SCHEMBL11592353 | 0.79 | KMT2A (0.48) | ALOX15GRIN2BKMT2ACYP2D6CYP1A2 | |
| SCHEMBL13008873 | 0.78 | SLC6A2 (0.38) | ALOX15KMT2ACYP2D6LMNAMEN1 | |
| SCHEMBL6299647 | 0.77 | KMT2A (0.39) | KMT2ACYP2D6 | |
| SCHEMBL8182568 | 0.76 | KMT2A (0.35) | KMT2ACYP2D6 | |
| SCHEMBL6809943 | 0.76 | KMT2A (0.37) | ALOX15KMT2ACYP2D6LMNAOPRM1 | |
| SCHEMBL3627121 | 0.75 | GSR (0.38) | ALOX15KMT2ACYP2D6CYP1A2HIF1A | |
| SCHEMBL4985361 | 0.75 | DHFR (0.41) | KMT2AKDM4EGAAMEN1MGAM | |
| SCHEMBL13008743 | 0.74 | KMT2A (0.33) | KMT2ACYP2D6 | |
| SCHEMBL9042599 | 0.73 | KMT2A (0.33) | KMT2ACYP2D6GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6420463-B1 | HEAT RESISTANCE, OXIDATION RESISTANCE OR PHOTOSTABILITY | CIBA SPECIALTY CHEMICALS CORP. | 2002-07-16 | — | — | US | claimed |
| US-6420562-B2 | OXIDATION, HEAT AND RADIATION RESISTANCE | CIBA SPECIALITY CHEMICALS CORPORATION | 2002-07-16 | — | — | US | claimed |