Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.35 |
| ▸ | TRPA1 | O75762 | 3/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.33 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | GFER | P55789 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7743245 | 0.87 | ALOX15 (0.41) | KMT2ACYP2D6OPRM1OPRD1KDM4E | |
| SCHEMBL4982859 | 0.81 | TAAR1 (0.38) | TAAR1TRPA1ALDH1A1KDM4EGFER | |
| SCHEMBL6809943 | 0.78 | KMT2A (0.37) | KMT2ACYP2D6TSHRHSD11B1OPRM1 | |
| SCHEMBL13008873 | 0.77 | SLC6A2 (0.38) | KMT2ACYP2D6TSHROPRM1OPRD1 | |
| SCHEMBL13008743 | 0.76 | KMT2A (0.33) | KMT2ACYP2D6 | |
| SCHEMBL8182568 | 0.75 | KMT2A (0.35) | KMT2ACYP2D6 | |
| SCHEMBL3627121 | 0.74 | GSR (0.38) | KMT2ACYP2D6TSHR | |
| SCHEMBL4985361 | 0.74 | DHFR (0.41) | KMT2ATSHRALDH1A1KDM4E | |
| SCHEMBL886985 | 0.73 | KMT2A (0.35) | KMT2ACYP2D6TSHRHSD11B1OPRM1 | |
| SCHEMBL4801749 | 0.73 | KMT2A (0.35) | KMT2ACYP2D6TSHRHSD11B1OPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7388052-B2 | Process for the preparation of block copolymers | POLIMERI EUROPA S.P.A. (IT) | 2008-06-17 | — | — | US | disclosed |
| EP-1519970-B1 | PROCESS FOR THE PREPARATION OF BLOCK COPOLYMERS | POLIMERI EUROPA SPA (IT) | 2007-10-24 | — | — | EP | disclosed |
| US-20070219329-A1 | polymerizing styrene using a nitroxy free radical catalyst, then adding methacrylonitrile; 2-methyl-2-(2,2,6,6-tetramethylpiperidin-1-yloxy)propionitrile catalyst; | POLIMERI EUROPA S.P.A. (IT) | 2007-09-20 | — | — | US | disclosed |