Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 5/20 | 0.70 |
| ▸ | TP53 | P04637 | 1/20 | 0.62 |
| ▸ | TSHR | P16473 | 1/20 | 0.62 |
| ▸ | PLA2G4B | P0C869 | 7/20 | 0.61 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | PTGES | O14684 | 1/20 | 0.53 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.53 |
| ▸ | PPARG | P37231 | 1/20 | 0.53 |
| ▸ | PPARA | Q07869 | 1/20 | 0.53 |
| ▸ | PTPN11 | Q06124 | 2/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11445003 | 0.88 | TP53 (0.68) | RARBTP53TSHRPLA2G4BPLA2G4A | |
| SCHEMBL8081583 | 0.87 | RARB (0.90) | RARBTP53TSHRPLA2G4BPLA2G4A | |
| SCHEMBL7336812 | 0.87 | RARB (0.90) | RARBTP53TSHRPLA2G4BPLA2G4A | |
| SCHEMBL6302467 | 0.84 | ALOX5 (0.59) | RARBMAPK1PTGESALOX5PPARG | |
| SCHEMBL3074389 | 0.84 | RARB (0.97) | RARBTP53TSHRPLA2G4BPLA2G4A | |
| SCHEMBL2490183 | 0.84 | RARB (0.97) | RARBTP53TSHRPLA2G4BPLA2G4A | |
| SCHEMBL9868849 | 0.83 | TP53 (0.69) | RARBTP53TSHRPLA2G4BPLA2G4A | |
| SCHEMBL8532269 | 0.83 | RARB (1.00) | RARBTP53TSHRPLA2G4BPLA2G4A | |
| SCHEMBL641904 | 0.83 | RARB (1.00) | RARBTP53TSHRPLA2G4BPLA2G4A | |
| SCHEMBL5858775 | 0.83 | RARB (1.00) | RARBTP53TSHRPLA2G4BPLA2G4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6265536-B1 | MICROBIOCIDE AND FUNGICIDE WHICH IS INHIBITOR OF BETA-1,3-GLUCAN SYNTHASE; TREATMENT OF PNEUMOCYSTIS CARINII INFECTION | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-07-24 | — | — | US | disclosed |