SCHEMBL2490183

SCHEMBL2490183

CCCCCOc1ccc(-c2ccc(C(=O)O)cc2)cc1

nearest known ligand 0.97

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
RARB P10826 5/20 0.97
TP53 P04637 1/20 0.87
TSHR P16473 1/20 0.87
PLA2G4B P0C869 8/20 0.84
PLA2G4A P47712 1/20 0.75
PTPN11 Q06124 2/20 0.68
HTT P42858 1/20 0.65

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3074389 1.00 RARB (0.97) RARBTP53TSHRPLA2G4BPLA2G4A
SCHEMBL8943017 0.98 RARB (1.00) RARBTP53TSHRPLA2G4BPLA2G4A
SCHEMBL8535621 0.98 RARB (1.00) RARBTP53TSHRPLA2G4BPLA2G4A
SCHEMBL2354189 0.98 RARB (1.00) RARBTP53TSHRPLA2G4BPLA2G4A
SCHEMBL7172427 0.98 RARB (1.00) RARBTP53TSHRPLA2G4BPLA2G4A
SCHEMBL4185457 0.98 RARB (1.00) RARBTP53TSHRPLA2G4BPLA2G4A
SCHEMBL641904 0.98 RARB (1.00) RARBTP53TSHRPLA2G4BPLA2G4A
SCHEMBL5828640 0.98 RARB (1.00) RARBTP53TSHRPLA2G4BPLA2G4A
SCHEMBL5858775 0.98 RARB (1.00) RARBTP53TSHRPLA2G4BPLA2G4A
SCHEMBL8532269 0.98 RARB (1.00) RARBTP53TSHRPLA2G4BPLA2G4A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115160098-B Oxygen-containing compound deoxidization methylation method 中国科学院兰州化学物理研究所 2023-06-06 CN disclosed
CN-115160098-A Oxygen-containing compound deoxidation and methylation method 中国科学院兰州化学物理研究所 2022-10-11 CN disclosed
US-9939555-B2 Cinnamic acid derivative, polymer thereof, and liquid crystal alignment layer comprising cured product thereof DIC CORPORATION (JP) 2018-04-10 US disclosed
US-20150337013-A1 NOVEL ANTIBACTERIAL AGENTS FOR THE TREATMENT OF GRAM POSITIVE INFECTIONS MERCK SHARP & DOHME CORP. (US) 2015-11-26 US disclosed
EP-2727947-A1 COPOLYMER, AND LIQUID CRYSTAL ALIGNMENT LAYER COMPRISING HARDENED PRODUCT THEREOF DIC Corporation (JP) 2014-05-07 EP disclosed
US-20140073558-A1 NOVEL ANTIBACTERIAL AGENTS FOR THE TREATMENT OF GRAM POSITIVE INFECTIONS CUBIST PHARMACEUTICALS, INC. (US) 2014-03-13 US disclosed
EP-2674437-A1 Novel antibacterial agents for the treatment of GRAM positive infections Cubist Pharmaceuticals, Inc. (US) 2013-12-18 EP disclosed
EP-2379580-B1 NOVEL ANTIBACTERIAL AGENTS FOR THE TREATMENT OF GRAM POSITIVE INFECTIONS CUBIST PHARM INC (US) 2013-10-23 EP disclosed
US-8507647-B2 Antibacterial agents for the treatment of gram positive infections CUBIST PHARMACEUTICALS, INC. (US) 2013-08-13 US disclosed
EP-2379580-A1 NOVEL ANTIBACTERIAL AGENTS FOR THE TREATMENT OF GRAM POSITIVE INFECTIONS Cubist Pharmaceuticals, Inc. (US) 2011-10-26 EP disclosed
US-5569646-A TREATMENT OF PNEUMONIA; MICROBIOCIDES, FUNGICIDES FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1996-10-29 US disclosed
US-5412144-A Organic materials with nonlinear optical properties THE BOARD OF TRUSTEES OF THE UNIV. OF ILLINOIS (US) 1995-05-02 US disclosed
EP-0644199-A1 Cyclic antimicrobial peptides and preparation thereof FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1995-03-22 EP disclosed
EP-0640676-A1 Mesomorphic compound, liquid crystal composition containing the compound, liquid crystal device using the composition, liquid crystal apparatus and display method CANON KABUSHIKI KAISHA (JP) 1995-03-01 EP disclosed
EP-0311329-B1 Liquid crystal compositions comprising optically active 1-[2-halogen-substituted-phenyl]-ethanols and derivatives thereof CHISSO CORP (JP) 1994-05-04 EP disclosed
US-4904409-A LIQUID CRYSTAL HAS HIGH TWISTABILITY CHISSO CORPORATION (JP) 1990-02-27 US disclosed
EP-0311329-A2 Liquid crystal compositions comprising optically active 1-[2-halogen-substituted-phenyl]-ethanols and derivatives thereof Chisso Corporation (JP) 1989-04-12 EP disclosed
US-4225454-A Ortho-cyanophenyl biphenylcarboxylate liquid crystal esters and mixtures thereof HUGHES AIRCRAFT COMPANY (US) 1980-09-30 US disclosed
US-4136053-A BIPHENYL ESTERS AND LIQUID CRYSTALLINE MIXTURES COMPRISING THEM MERCK PATENT GESELLSCHAFT MIT BESCHANKTER HAFTUNG (DE) 1979-01-23 US disclosed
US-4065489-A Biphenyl esters and liquid crystalline mixtures comprising them MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DT) 1977-12-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150337013-A1 NOVEL ANTIBACTERIAL AGENTS FOR THE TREATMENT OF GRAM POSITIVE INFECTIONS CLPP, CLPTM1, RPN1 RARB 4537/4885TP53 4408/4885TSHR 4677/4885
US-20140073558-A1 NOVEL ANTIBACTERIAL AGENTS FOR THE TREATMENT OF GRAM POSITIVE INFECTIONS CLPP, CLPTM1, RPN1 RARB 4537/4885TP53 4408/4885TSHR 4677/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.