Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 4/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.35 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.35 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.35 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.35 |
| ▸ | ESR1 | P03372 | 1/20 | 0.34 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.34 |
| ▸ | ANPEP | P15144 | 1/20 | 0.34 |
| ▸ | LAP3 | P28838 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.33 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.32 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.32 |
| ▸ | MAOB | P27338 | 1/20 | 0.32 |
| ▸ | DPP4 | P27487 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8339719 | 0.89 | NR1H2 (0.38) | SLC6A4ESR1NR1H2NR1H3 | |
| SCHEMBL28591973 | 0.83 | TAAR1 (0.40) | MAOASLC6A2TAAR1SLC6A4SLC6A3 | |
| SCHEMBL14977000 | 0.82 | CSNK1E (0.33) | — | |
| SCHEMBL16177937 | 0.80 | CSNK1E (0.38) | — | |
| SCHEMBL6003566 | 0.80 | SLC6A2 (0.32) | MAOASLC6A2TAAR1SLC6A4SLC6A3 | |
| SCHEMBL27550597 | 0.80 | MAOA (0.37) | MAOASLC6A2TAAR1SLC6A4SLC6A3 | |
| SCHEMBL2244551 | 0.78 | SLC6A2 (0.32) | MAOASLC6A2TAAR1SLC6A4SLC6A3 | |
| SCHEMBL14976317 | 0.77 | CSNK1E (0.46) | — | |
| SCHEMBL2832122 | 0.76 | SLC6A2 (0.31) | MAOASLC6A2TAAR1SLC6A4SLC6A3 | |
| SCHEMBL2012876 | 0.75 | SLC6A2 (0.39) | MAOASLC6A2TAAR1SLC6A4SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2782920-B1 | FUNGICIDE N-[(TRISUBSTITUTEDSILYL)METHYL]-CARBOXAMIDE DERIVATIVES | BAYER IP GMBH (DE) | 2016-12-21 | — | — | EP | claimed |
| US-20140315858-A1 | FUNGICIDE N-[(TRISUBSTITUTEDSILYL)METHYL]-CARBOXAMIDE DERIVATIVES | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2014-10-23 | — | — | US | claimed |
| CN-102351174-A | Preparation method of dispersible silane functionalized graphene | UNIV SOUTH CHINA TECH | 2012-02-15 | — | — | CN | claimed |
| EP-0929841-A4 | METHOD FOR FORMING PHOTORESIST FEATURES HAVING REENTRANT PROFILES USING A BASIC AGENT | MKE QUANTUM COMPONENTS COLORAD (US) | 2001-04-18 | — | — | EP | claimed |
| US-5955244-A | Method for forming photoresist features having reentrant profiles using a basic agent | QUANTUM CORPORATION (US) | 1999-09-21 | — | — | US | claimed |
| EP-0929841-A1 | METHOD FOR FORMING PHOTORESIST FEATURES HAVING REENTRANT PROFILES USING A BASIC AGENT | Mke-Quantum Components Colorado LLC (US) | 1999-07-21 | — | — | EP | claimed |
| WO-1998008143-A1 | METHOD FOR FORMING PHOTORESIST FEATURES HAVING REENTRANT PROFILES USING A BASIC AGENT | MKE-QUANTUM COMPONENTS COLORADO LLC (US) | 1998-02-26 | — | — | WO | claimed |
| US-9617286-B2 | Fungicide N-[(trisubstitutedsilyl)methyl]-carboxamide derivatives | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2017-04-11 | — | — | US | disclosed |
| EP-2782920-B1 | FUNGICIDE N-[(TRISUBSTITUTEDSILYL)METHYL]-CARBOXAMIDE DERIVATIVES | BAYER IP GMBH (DE) | 2016-12-21 | — | — | EP | disclosed |
| US-20140315858-A1 | FUNGICIDE N-[(TRISUBSTITUTEDSILYL)METHYL]-CARBOXAMIDE DERIVATIVES | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2014-10-23 | — | — | US | disclosed |
| CN-102351174-A | Preparation method of dispersible silane functionalized graphene | UNIV SOUTH CHINA TECH | 2012-02-15 | — | — | CN | disclosed |
| EP-0929841-A4 | METHOD FOR FORMING PHOTORESIST FEATURES HAVING REENTRANT PROFILES USING A BASIC AGENT | MKE QUANTUM COMPONENTS COLORAD (US) | 2001-04-18 | — | — | EP | disclosed |
| US-5955244-A | Method for forming photoresist features having reentrant profiles using a basic agent | QUANTUM CORPORATION (US) | 1999-09-21 | — | — | US | disclosed |
| US-4822830-A | CROSSLINKED WITH AMINOORGANOSILICON COMPOUND AND ALUMINA TRIHYDRATE; MOISTURE CURED | WACKER SILICONES CORPORATION (US) | 1989-04-18 | — | — | US | disclosed |
| EP-0017734-B1 | CURABLE ORGANOPOLYSILOXANE COMPOSITIONS CONTAINING CARBON BLACK, METHOD FOR PREPARING THE SAME AND METHOD FOR CURING THE COMPOSITIONS | SWS Silicones Corporation (US) | 1983-04-13 | — | — | EP | disclosed |
| US-4301056-A | OBTAINED BY CROSSLINKING A POLYSILOXANE, ORGANIC PEROXIDE, AND A HYDROPHOBIC CALCIUM HYDROXIDE | WACKER-CHEMIE GMBH (DE) | 1981-11-17 | — | — | US | disclosed |
| EP-0017734-A1 | Curable organopolysiloxane compositions containing carbon black, method for preparing the same and method for curing the compositions | SWS Silicones Corporation (US) | 1980-10-29 | — | — | EP | disclosed |
| US-4221693-A | ROOM TEMPERATURE VULCANIZED SILICONE RUBBERS | WACKER SILICONES CORPORATION | 1980-09-09 | — | — | US | disclosed |
| US-4184880-A | RELEASE AGENTS | WACKER-CHEMIE GMBH (DE) | 1980-01-22 | — | — | US | disclosed |
| US-4111890-A | CURABLE ORGANOPOLYSILOXANE COMPOSITIONS CONTAINING TITANIUM ESTERS | SWS SILICONES CORPORATION (US) | 1978-09-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140315858-A1 | FUNGICIDE N-[(TRISUBSTITUTEDSILYL)METHYL]-CARBOXAMIDE DERIVATIVES | TET3, TET1, PFAS | MAOA 1898/4885SLC6A2 3457/4885TAAR1 3044/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.