Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.44 |
| ▸ | MEN1 | O00255 | 5/20 | 0.44 |
| ▸ | MAPT | P10636 | 5/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | HTT | P42858 | 3/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.44 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.44 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | XBP1 | P17861 | 1/20 | 0.44 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.44 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | FABP7 | O15540 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | APEX1 | P27695 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9519629 | 0.81 | MAPT (0.54) | KMT2AMEN1MAPTLMNAHTT | |
| SCHEMBL3631342 | 0.81 | MAPT (0.54) | KMT2AMEN1MAPTLMNAHTT | |
| SCHEMBL28390146 | 0.78 | HCAR2 (0.45) | KMT2AMEN1MAPTLMNASMN1; SMN2 | |
| SCHEMBL20590123 | 0.74 | EPHX2 (0.45) | KMT2AMEN1MAPTLMNAHTT | |
| SCHEMBL10805796 | 0.74 | EPHX2 (0.45) | KMT2AMEN1MAPTLMNAHTT | |
| SCHEMBL9244671 | 0.74 | MAOB (0.55) | KMT2AMEN1MAPTLMNAHTT | |
| SCHEMBL9297637 | 0.74 | POLB (0.49) | KMT2AMEN1MAPTLMNAHTT | |
| SCHEMBL9244660 | 0.74 | MAOB (0.55) | KMT2AMEN1MAPTLMNAHTT | |
| SCHEMBL4354147 | 0.73 | SMN1; SMN2 (0.55) | KMT2AMEN1MAPTLMNAHTT | |
| SCHEMBL28476057 | 0.72 | MAOB (0.42) | KMT2AMEN1MAPTLMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6423866-B1 | THERMOLYSIS OF AMMONIUM SALT OF HALOGENATED LOWER ALKYL ACETOACETATE USING MELT | SOLVAYTFLOUR UND DERIVATE GMBH (DE) | 2002-07-23 | — | — | US | disclosed |