Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.62 |
| ▸ | TXNRD3 | Q86VQ6 | 1/20 | 0.62 |
| ▸ | TXNRD2 | Q9NNW7 | 1/20 | 0.62 |
| ▸ | MAPT | P10636 | 10/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.38 |
| ▸ | MEN1 | O00255 | 4/20 | 0.38 |
| ▸ | POLB | P06746 | 3/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | MTOR | P42345 | 1/20 | 0.38 |
| ▸ | VCP | P55072 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1426690 | 0.87 | TXNRD1 (0.66) | TXNRD1TXNRD3TXNRD2MAPTKMT2A | |
| SCHEMBL4994296 | 0.84 | TXNRD1 (0.62) | TXNRD1TXNRD3TXNRD2MAPTKMT2A | |
| SCHEMBL5239589 | 0.79 | TXNRD1 (0.68) | TXNRD1TXNRD3TXNRD2MAPTKMT2A | |
| SCHEMBL1613615 | 0.79 | TXNRD1 (0.55) | TXNRD1TXNRD3TXNRD2MAPTKMT2A | |
| SCHEMBL5238946 | 0.79 | TXNRD1 (0.55) | TXNRD1TXNRD3TXNRD2MAPTKMT2A | |
| SCHEMBL3328445 | 0.78 | TXNRD1 (0.66) | TXNRD1TXNRD3TXNRD2MAPTKMT2A | |
| SCHEMBL773992 | 0.76 | TXNRD1 (0.68) | TXNRD1TXNRD3TXNRD2MAPTKMT2A | |
| SCHEMBL6364031 | 0.75 | TXNRD1 (0.62) | TXNRD1TXNRD3TXNRD2MAPTKMT2A | |
| SCHEMBL12932125 | 0.75 | TXNRD1 (0.62) | TXNRD1TXNRD3TXNRD2MAPTKMT2A | |
| SCHEMBL5234315 | 0.73 | TXNRD1 (0.64) | TXNRD1TXNRD3TXNRD2MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8637434-B2 | System for photolithographic synthesis of polymer arrays | AFFYMETRIX, INC. (US) | 2014-01-28 | — | — | US | disclosed |
| US-20130059763-A1 | System for photolithographic synthesis of polymer arrays | AFFYMETRIX, INC. (US) | 2013-03-07 | — | — | US | disclosed |
| US-8309496-B2 | Methods for photolithographic synthesis of polymer arrays utilizing anti-reflective coatings | AFFYMETRIX, INC. (US) | 2012-11-13 | — | — | US | disclosed |
| US-20120071361-A1 | Substrate Preparation Process | AFFYMETRIX, INC. (US) | 2012-03-22 | — | — | US | disclosed |
| US-8067578-B2 | Substrate preparation process | AFFYMETRIX, INC. (US) | 2011-11-29 | — | — | US | disclosed |
| US-20100331217-A1 | SUBSTRATE PREPARATION PROCESS | AFFYMETRIX, INC. (US) | 2010-12-30 | — | — | US | disclosed |
| US-20100298171-A1 | APPARATUS FOR POLYMER SYNTHESIS | AFFYMETRIX, INC. (US) | 2010-11-25 | — | — | US | disclosed |
| US-20060160099-A1 | Substrate preparation process | AFFYMETRIX, INC. (US) | 2006-07-20 | — | — | US | disclosed |
| US-20060008840-A1 | Substrate preparation process | AFFYMETRIX, INC. (US) | 2006-01-12 | — | — | US | disclosed |
| US-20050181396-A1 | Substrate preparation process | AFFYMETRIX, INC. (US) | 2005-08-18 | — | — | US | disclosed |
| US-20050181431-A1 | Flow device for preparation of microarrays comprising positionally distinct polymer sequences; high throughput assay | AFFYMETRIX, INC. (US) | 2005-08-18 | — | — | US | disclosed |
| EP-0950112-A4 | PHOTOLABILE POLYMER ARRAY SYNTHESIS METHODS | AFFYMETRIX INC (US) | 2004-12-15 | — | — | EP | disclosed |
| US-6706875-B1 | PREPARING SOLID SUBSTRATE FOR FORMING POLYMER SEQUENCES THEREON BY PROVIDING FUNCTIONAL GROUPS ON SURFACE OF SUBSTRATE AND COUPLING MONOMERS INCLUDING LIPOPHILIC PHOSPHORAMIDITE GROUPS TO FUNCTIONAL GROUPS | AFFYEMTRIX, INC. | 2004-03-16 | — | — | US | disclosed |
| US-6307042-B1 | GENERATING NUCLEOTIDE SEQUENCES; PROVIDE SUBSTRATE WAFERS, REMOVE PROTECTED GROUPS, TRANSFER SUBSTRATE WAFERS TO COUPLING STATION, TRANSFER SUBSTRATE WAFER TO ACTIVATION STATION, ANALYZE POLYMER LAYOUTS | AFFYMETRIX, INC. | 2001-10-23 | — | — | US | disclosed |
| EP-0950112-A1 | PHOTOLABILE POLYMER ARRAY SYNTHESIS METHODS | Affymetrix, Inc. (a California Corporation) (US) | 1999-10-20 | — | — | EP | disclosed |
| US-5959098-A | ACTIVATING AND COUPLING MONOMERS IN DIFFERENT SELECTED ZONES OF SUBSTRATE FORMING DIFFERENT SEQUENCES IN DIFFERENT AREAS; ACTIVATING BY DIRECTING RADIATION AT SURFACE OF SUBSTRATE WITH FUNCTIONAL GROUPS PROTECTED BY PHOTOLABILE GROUPS | AFFYMETRIX, INC. (US) | 1999-09-28 | — | — | US | disclosed |
| WO-1997039151-A1 | PHOTOLABILE POLYMER ARRAY SYNTHESIS METHODS | AFFYMETRIX, INC. (US) | 1997-10-23 | — | — | WO | disclosed |