Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.55 |
| ▸ | TXNRD3 | Q86VQ6 | 1/20 | 0.55 |
| ▸ | TXNRD2 | Q9NNW7 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | AR | P10275 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 2/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1426690 | 0.81 | TXNRD1 (0.66) | TXNRD1TXNRD3TXNRD2MAPTKDM4E | |
| SCHEMBL774345 | 0.79 | TXNRD1 (0.62) | TXNRD1TXNRD3TXNRD2MAPTKDM4E | |
| SCHEMBL4994296 | 0.79 | TXNRD1 (0.62) | TXNRD1TXNRD3TXNRD2MAPTKDM4E | |
| SCHEMBL5238946 | 0.78 | TXNRD1 (0.55) | TXNRD1TXNRD3TXNRD2MAPTKDM4E | |
| SCHEMBL5859861 | 0.77 | KDM4E (0.50) | MAPTKDM4ECYP1A2HSD17B10KMT2A | |
| SCHEMBL5859863 | 0.77 | KDM4E (0.50) | MAPTKDM4ECYP1A2HSD17B10KMT2A | |
| SCHEMBL29901773 | 0.77 | TXNRD1 (0.64) | TXNRD1TXNRD3TXNRD2MAPTKDM4E | |
| SCHEMBL1613587 | 0.76 | MAPT (0.55) | MAPTKDM4ECYP1A2KMT2ATDP1 | |
| SCHEMBL12004153 | 0.76 | MAPT (0.55) | MAPTKDM4ECYP1A2KMT2ATDP1 | |
| SCHEMBL1613586 | 0.76 | MAPT (0.55) | MAPTKDM4ECYP1A2KMT2ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130017582-A1 | ENHANCED PRODUCTION OF TAXOL AND TAXANES BY CELL CULTURES OF TAXUS SPECIES | PHYTON HOLDINGS, LLC (US) | 2013-01-17 | — | — | US | disclosed |
| US-20110086397-A1 | ENHANCED PRODUCTION OF TAXOL AND TAXANES BY CELL CULTURES OF TAXUS SPECIES | PHYTON HOLDINGS, LLC (US) | 2011-04-14 | — | — | US | disclosed |
| US-20080108115-A1 | ENHANCED PRODUCTION OF TAXOL AND TAXANES BY CELL CULTURES OF TAXUS SPECIES | DFB BIOTECH, INCORPORATED (US) | 2008-05-08 | — | — | US | disclosed |
| US-7264951-B1 | Enhanced production of taxol and taxanes by cell cultures of Taxus species | PHYTON, INC. (US) | 2007-09-04 | — | — | US | disclosed |