Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 5/20 | 0.49 |
| ▸ | BCHE | P06276 | 2/20 | 0.47 |
| ▸ | ACHE | P22303 | 2/20 | 0.47 |
| ▸ | CCKBR | P32239 | 2/20 | 0.45 |
| ▸ | NMBR | P28336 | 2/20 | 0.45 |
| ▸ | TACR2 | P21452 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7745638 | 0.85 | TACR1 (0.50) | TACR1CCKBRNMBR | |
| SCHEMBL7742410 | 0.85 | KMT2A (0.52) | TACR1CCKBRNMBR | |
| SCHEMBL7743627 | 0.83 | TACR1 (0.51) | TACR1CCKBRNMBR | |
| SCHEMBL7742356 | 0.81 | TACR1 (0.58) | TACR1BCHEACHENMBR | |
| SCHEMBL7743655 | 0.78 | TACR1 (0.46) | TACR1CCKBRNMBR | |
| SCHEMBL7742501 | 0.78 | TACR1 (0.46) | TACR1CCKBRNMBR | |
| SCHEMBL7743562 | 0.76 | TACR1 (0.50) | TACR1BCHEACHETACR2 | |
| SCHEMBL7737704 | 0.74 | TACR1 (0.58) | TACR1NMBR | |
| SCHEMBL8816203 | 0.74 | KMT2A (0.48) | TACR1TACR2 | |
| SCHEMBL7745643 | 0.73 | TACR1 (0.59) | TACR1BCHENMBR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0819005-A4 | 2-ACYLAMINOPROPANAMIDES AS TACHYKININ RECEPTOR ANTAGONISTS | LILLY CO ELI (US) | 2001-03-21 | — | — | EP | claimed |
| EP-0819005-A1 | 2-ACYLAMINOPROPANAMIDES AS TACHYKININ RECEPTOR ANTAGONISTS | ELI LILLY AND COMPANY (US) | 1998-01-21 | — | — | EP | claimed |
| WO-1997006803-A1 | 2-ACYLAMINOPROPANAMIDES AS GROWTH HORMONE SECRETAGOGUES | ELI LILLY AND COMPANY (US) | 1997-02-27 | — | — | WO | claimed |
| WO-1996031214-A1 | 2-ACYLAMINOPROPANAMIDES AS TACHYKININ RECEPTOR ANTAGONISTS | ELI LILLY AND COMPANY (US) | 1996-10-10 | — | — | WO | claimed |