⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28380914 | 0.74 | SMPD1 (0.30) | — | |
| SCHEMBL22367664 | 0.74 | — | — | |
| SCHEMBL7906814 | 0.72 | — | — | |
| SCHEMBL6854956 | 0.69 | — | — | |
| SCHEMBL442365 | 0.67 | — | — | |
| SCHEMBL7743643 | 0.66 | TSHR (0.32) | — | |
| SCHEMBL7454401 | 0.65 | TSHR (0.35) | — | |
| SCHEMBL10495860 | 0.61 | — | — | |
| SCHEMBL8191870 | 0.61 | TSHR (0.32) | — | |
| SCHEMBL27294287 | 0.61 | TSHR (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118234862-A | Modified short interfering nucleic acid molecules (siNA) and uses thereof | 阿利戈斯治疗公司 | 2024-06-21 | — | — | CN | disclosed |
| CN-116916963-A | Multivalent ligand clusters with diamine scaffolds for targeted delivery of therapeutic agents | 上海舶望制药有限公司 | 2023-10-20 | — | — | CN | disclosed |
| CN-114585737-A | Oligonucleotide compositions and methods of use thereof | 波涛生命科学有限公司 | 2022-06-03 | — | — | CN | disclosed |
| CN-109694397-B | Cyclic dinucleotide compounds, preparation method and application thereof | 上海弘翊生物科技有限公司 | 2021-08-31 | — | — | CN | disclosed |