Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 6/20 | 0.39 |
| ▸ | MAOA | P21397 | 5/20 | 0.39 |
| ▸ | KDM1A | O60341 | 4/20 | 0.33 |
| ▸ | BCHE | P06276 | 1/20 | 0.33 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.33 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
| ▸ | HTR6 | P50406 | 1/20 | 0.33 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16192661 | 0.78 | HDAC9 (0.35) | MAOBMAOAHDAC9KMT2AALDH1A1 | |
| SCHEMBL1988667 | 0.77 | MAOA (0.35) | MAOBMAOAMEN1KMT2A | |
| SCHEMBL4946111 | 0.74 | ACHE (0.41) | MAOBMAOABCHEACHE | |
| SCHEMBL2028968 | 0.72 | SIGMAR1 (0.38) | KMT2ASIGMAR1 | |
| SCHEMBL7947368 | 0.71 | MAOB (0.41) | MAOBMAOAKDM1ABCHEADRA2B | |
| SCHEMBL5807645 | 0.71 | KDM1A (0.40) | MAOBMAOAKDM1ABCHEADRA2B | |
| SCHEMBL4348712 | 0.71 | MAOB (0.38) | MAOBMAOAKDM1ABCHEADRA2B | |
| SCHEMBL7341859 | 0.71 | MAOB (0.38) | MAOBMAOAKDM1ABCHEADRA2B | |
| SCHEMBL6472053 | 0.69 | ACHE (0.38) | KDM1AACHEMEN1KMT2A | |
| SCHEMBL7743674 | 0.69 | KDM1A (0.41) | MAOBKDM1AHDAC9MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118141772-A | Ropinirole Luo Jia hydrochloride sulfonic acid rasagiline compound orally disintegrating controlled release tablet and preparation method thereof | 四川鲁徽制药有限责任公司 | 2024-06-07 | — | — | CN | disclosed |
| CN-116082166-A | Preparation method of rasagiline mesylate | 上海复旦复华药业有限公司 | 2023-05-09 | — | — | CN | disclosed |
| CN-110776429-B | Improved preparation method of rasagiline racemic intermediate | 齐鲁制药有限公司 | 2022-12-02 | — | — | CN | disclosed |
| CN-110776429-A | Improved preparation method of rasagiline racemic intermediate | 齐鲁制药有限公司 | 2020-02-11 | — | — | CN | disclosed |
| CN-102786422-B | Method for preparing rasagiline mesylate | TOPHARMAN SHANGHAI CO LTD | 2015-02-25 | — | — | CN | disclosed |
| CN-102786422-B | Method for preparing rasagiline mesylate | TOPHARMAN SHANGHAI CO LTD | 2015-02-25 | — | — | CN | disclosed |
| US-8741962-B2 | Process for preparation of Rasagiline and salts thereof | USV LIMITED (IN) | 2014-06-03 | — | — | US | disclosed |
| WO-2013168032-A1 | PHARMACEUTICAL COMPOSITIONS COMPRISING RASAGILINE | MICRO LABS LIMITED (IN) | 2013-11-14 | — | — | WO | disclosed |
| EP-2657221-A1 | Preparation of rasagiline and salts thereof | Dr. Reddy's Laboratories Ltd. (IN) | 2013-10-30 | — | — | EP | disclosed |
| CN-102786422-A | Method for preparing rasagiline mesylate | TOPHARMAN SHANGHAI CO LTD | 2012-11-21 | — | — | CN | disclosed |
| EP-2364967-A2 | Process for preparation of rasagiline and salts thereof | USV Limited (IN) | 2011-09-14 | — | — | EP | disclosed |
| US-20110218360-A1 | PREPARATION OF RASAGILINE AND SALTS THEREOF | DR. REDDY'S LABORATORIES LTD. (IN) | 2011-09-08 | — | — | US | disclosed |
| EP-2358658-A2 | PREPARATION OF RASAGILINE AND SALTS THEREOF | Dr. Reddy's Laboratories, Ltd. (IN) | 2011-08-24 | — | — | EP | disclosed |
| US-20110155626-A1 | PROCESS FOR PREPARATION OF RASAGILINE AND SALTS THEREOF | USV LIMITED (IN) | 2011-06-30 | — | — | US | disclosed |
| US-20110015274-A1 | FORM OF AN AMINOINDAN MESYLATE DERIVATIVE | MEDICHEM, S.A. (ES) | 2011-01-20 | — | — | US | disclosed |
| WO-2010111264-A2 | RASAGILINE FORMULATIONS | DR. REDDY'S LABORATORIES LTD. (IN) | 2010-09-30 | — | — | WO | disclosed |
| WO-2010059913-A2 | PREPARATION OF RASAGILINE AND SALTS THEREOF | DR. REDDY'S LABORATORIES LTD. (IN) | 2010-05-27 | — | — | WO | disclosed |
| US-20100041920-A1 | NEW SALT FORMS OF AN AMINOINDAN DERIVATIVE | MEDICHEM, S.A. (ES) | 2010-02-18 | — | — | US | disclosed |
| US-20090247537-A1 | METHODS FOR PREVENTING OR TREATING BRUXISM USING DOPAMINERGIC AGENTS | OVERFIELD WILLIAM DALE | 2009-10-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110015274-A1 | FORM OF AN AMINOINDAN MESYLATE DERIVATIVE | RAB29, RAB6A, QDPR | MAOB 491/4885MAOA 404/4885KDM1A 2691/4885 |
| US-20100041920-A1 | NEW SALT FORMS OF AN AMINOINDAN DERIVATIVE | RAB35, RAB7A, RAB10 | MAOB 2254/4885MAOA 1787/4885KDM1A 3588/4885 |
| US-20110155626-A1 | PROCESS FOR PREPARATION OF RASAGILINE AND SALTS THEREOF | RAB27A, RAB35, RAB7A | MAOB 365/4885MAOA 343/4885KDM1A 4069/4885 |
| US-20110218360-A1 | PREPARATION OF RASAGILINE AND SALTS THEREOF | RAB35, RAB27A, RAB5C | MAOB 423/4885MAOA 336/4885KDM1A 2115/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.