SCHEMBL7743702

SCHEMBL7743702

[c]1ncc2c(n1)sc1ccccc12

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GPR3 P46089 1/20 0.48
MAPT P10636 5/20 0.36
ALDH1A1 P00352 5/20 0.36
RAB9A P51151 2/20 0.36
HPGD P15428 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
LIMK1 P53667 1/20 0.32
CDK5 Q00535 1/20 0.32
CDK5R1 Q15078 1/20 0.32
LOXL2 Q9Y4K0 1/20 0.32
ALOX15 P16050 1/20 0.32
MEN1 O00255 2/20 0.31
KMT2A Q03164 2/20 0.31
KDM4E B2RXH2 2/20 0.31
GAA P10253 1/20 0.31
HIF1A Q16665 1/20 0.31
NPSR1 Q6W5P4 1/20 0.31
TDP1 Q9NUW8 1/20 0.31
ELANE P08246 1/20 0.31
PTGIR P43119 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL154291 0.79 GPR3 (0.52) GPR3MAPTALDH1A1RAB9AHPGD
SCHEMBL18173729 0.73 GPR3 (0.48) GPR3MAPTALDH1A1RAB9AHPGD
SCHEMBL29717311 0.73 GPR3 (0.48) GPR3MAPTALDH1A1RAB9AHPGD
SCHEMBL3038100 0.73 GPR3 (0.48) GPR3MAPTALDH1A1RAB9AHPGD
SCHEMBL18687114 0.71 LMNA (0.35) MAPTALDH1A1L3MBTL1
SCHEMBL3965351 0.70 CLK1 (0.42) MAPTALDH1A1RAB9AHPGDLIMK1
SCHEMBL843168 0.69 GPR3 (0.54) GPR3MAPTALDH1A1RAB9AHPGD
Dibenzothiophene SCHEMBL14659543 0.68 GPR3 (1.00) GPR3MAPTALDH1A1RAB9AHPGD
Dibenzothiophene SCHEMBL30167635 0.68 GPR3 (1.00) GPR3MAPTALDH1A1RAB9AHPGD
Dibenzothiophene SCHEMBL13294 0.68 GPR3 (1.00) GPR3MAPTALDH1A1RAB9AHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180155325-A1 COMPOUND FOR ORGANIC OPTOELECTRONIC DEVICE, COMPOSITION FOR ORGANIC OPTOELECTRONIC DEVICE AND ORGANIC OPTOELECTRONIC DEVICE AND DISPLAY DEVICE SAMSUNG SDI CO., LTD. (KR) 2018-06-07 US claimed
WO-2022147180-A1 HIGH REFRACTIVE INDEX OVERCOAT FORMULATION AND METHOD OF USE WITH INKJET PRINTING META PLATFORMS TECHNOLOGIES, LLC (US) 2022-07-07 WO disclosed
US-20180155325-A1 COMPOUND FOR ORGANIC OPTOELECTRONIC DEVICE, COMPOSITION FOR ORGANIC OPTOELECTRONIC DEVICE AND ORGANIC OPTOELECTRONIC DEVICE AND DISPLAY DEVICE SAMSUNG SDI CO., LTD. (KR) 2018-06-07 US disclosed
EP-1067123-A1 NITROGENOUS HETEROCYCLIC COMPOUNDS KYOWA HAKKO KOGYO CO., LTD. (JP) 2001-01-10 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180155325-A1 COMPOUND FOR ORGANIC OPTOELECTRONIC DEVICE, COMPOSITION FOR ORGANIC OPTOELECTRONIC DEVICE AND ORGANIC OPTOELECTRONIC DEVICE AND DISPLAY DEVICE OXER1, OCIAD1, OR10J3 GPR3 1242/4885MAPT 1820/4885ALDH1A1 60/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.