SCHEMBL7743739

SCHEMBL7743739

CCCCCCSCCC(=O)OCC

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DGKA P23743 1/20 0.50
CES2 O00748 3/20 0.48
MAPT P10636 2/20 0.48
GMNN O75496 1/20 0.48
TP53 P04637 1/20 0.48
POLB P06746 1/20 0.48
THRB P10828 1/20 0.48
CYP2C9 P11712 1/20 0.48
BLM P54132 1/20 0.48
HSD17B10 Q99714 1/20 0.48
PAM P19021 2/20 0.46
CYP1A2 P05177 1/20 0.46
PLA2G4B P0C869 1/20 0.45
TSHR P16473 2/20 0.45
ABL1 P00519 1/20 0.45
RIN1 Q13671 1/20 0.45
FAAH O00519 4/20 0.43
CES1 P23141 4/20 0.43
PLA2G6 O60733 1/20 0.43
DNM1 Q05193 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9496204 1.00 DGKA (0.50) DGKACES2MAPTGMNNTP53
SCHEMBL7743644 1.00 DGKA (0.50) DGKACES2MAPTGMNNTP53
SCHEMBL8897738 1.00 DGKA (0.50) DGKACES2MAPTGMNNTP53
SCHEMBL10504555 0.93 DGKA (0.55) DGKACES2MAPTGMNNTP53
SCHEMBL7747709 0.93 DGKA (0.55) DGKACES2MAPTGMNNTP53
SCHEMBL10502694 0.93 DGKA (0.60) DGKACES2MAPTGMNNTP53
SCHEMBL11661646 0.92 TSHR (0.50) DGKACES2MAPTGMNNTP53
SCHEMBL17364480 0.89 DGKA (0.66) DGKACES2MAPTGMNNTP53
SCHEMBL9763789 0.87 NAAA (0.58) DGKACES2MAPTGMNNTP53
SCHEMBL17107450 0.87 NAAA (0.58) DGKACES2MAPTGMNNTP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6184180-B1 COMPRISES SUPPORT, REVERSIBLE HEAT-SENSITIVE RECORDING LAYER CONTAINING DYE PRECURSOR WHICH IS COLORLESS OR A PALE COLOR, COLOR DEVELOPER CAPABLE OF CAUSING REVERSIBLE CHANGE IN COLOR DENSITY OF DYE DUE TO DIFFERENCE IN COOLING RATE MITSUBISHI PAPER MILLS LIMITED (JP) 2001-02-06 US disclosed
EP-0166509-B1 PHENOL DERIVATIVES IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1992-05-13 EP disclosed
US-4833135-A Antioestrogenic phenol derivatives IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1989-05-23 US disclosed
EP-0166509-A1 Phenol derivatives IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1986-01-02 EP disclosed
US-4076639-A 6,9-DIAZA-6,9-DIALKYL-4,11-DITHIA-5,10-DITHIOTETRADECANEDIOIC ACID ESTERS MOBIL OIL CORPORATION (US) 1978-02-28 US disclosed