Known targets — ChEMBL curated mechanism
ADRB1CDK4CDK6CHRM2CHRM3DPP4DRD2DRD3DRD4EGFRHRH1HTR1BHTR1DHTR1FHTR2AHTR2CHTR4SLC6A2SLC6A4
The experimentally established mechanism targets of Succinic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNM1 | Q05193 | 3/20 | 0.65 |
| ▸ | KDM4A | O75164 | 4/20 | 0.61 |
| ▸ | KDM4C | Q9H3R0 | 4/20 | 0.61 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.60 |
| ▸ | PPARG | P37231 | 7/20 | 0.60 |
| ▸ | PPARD | Q03181 | 7/20 | 0.60 |
| ▸ | PPARA | Q07869 | 7/20 | 0.60 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.60 |
| ▸ | TSHR | P16473 | 4/20 | 0.60 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.60 |
| ▸ | TLR2 | O60603 | 2/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.60 |
| ▸ | FABP4 | P15090 | 2/20 | 0.60 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.60 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.60 |
| ▸ | MEN1 | O00255 | 1/20 | 0.60 |
| ▸ | ESR1 | P03372 | 1/20 | 0.60 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.60 |
| ▸ | PDE4A | P27815 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Succinic Acid SCHEMBL7743788 | 1.00 | DNM1 (0.65) | DNM1KDM4AKDM4CGPR84PPARG | |
| Butyric Acid SCHEMBL4296264 | 0.94 | DNM1 (0.62) | DNM1KDM4AKDM4CGPR84PPARG | |
| Butyric Acid SCHEMBL4302171 | 0.94 | DNM1 (0.62) | DNM1KDM4AKDM4CGPR84PPARG | |
| Dymanthine SCHEMBL5881218 | 0.94 | GPR84 (0.71) | DNM1KDM4AKDM4CGPR84PPARG | |
| Heptanoate SCHEMBL3412845 | 0.94 | GPR84 (0.71) | DNM1KDM4AKDM4CGPR84PPARG | |
| Hexanoate SCHEMBL1628892 | 0.94 | GPR84 (0.71) | DNM1KDM4AKDM4CGPR84PPARG | |
| Stearic Acid SCHEMBL20142888 | 0.94 | GPR84 (0.71) | DNM1KDM4AKDM4CGPR84PPARG | |
| Octanoic Acid SCHEMBL3413793 | 0.94 | GPR84 (0.71) | DNM1KDM4AKDM4CGPR84PPARG | |
| Stearic Acid SCHEMBL20142324 | 0.94 | GPR84 (0.71) | DNM1KDM4AKDM4CGPR84PPARG | |
| Stearic Acid SCHEMBL20142251 | 0.94 | GPR84 (0.71) | DNM1KDM4AKDM4CGPR84PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1344136-A | Process and compsns. promotijng biological effectiveness of exogenous chemical substances in plants | MONSANTO CO (US) | 2002-04-10 | — | — | CN | disclosed |
| EP-1139737-A1 | PROCESS AND COMPOSITIONS PROMOTING BIOLOGICAL EFFECTIVENESS OF EXOGENOUS CHEMICAL SUBSTANCES IN PLANTS | Monsanto Technology LLC (US) | 2001-10-10 | — | — | EP | disclosed |
| US-20010019996-A1 | PROCESS AND COMPOSITIONS PROMOTING BIOLOGICAL EFFECTIVENESS OF EXOGENOUS CHEMICAL SUBSTANCES IN PLANTS | FLAMEL TECHNOLOGIES (FR) | 2001-09-06 | — | — | US | disclosed |
| WO-2000038514-A1 | PROCESS AND COMPOSITIONS PROMOTING BIOLOGICAL EFFECTIVENESS OF EXOGENOUS CHEMICAL SUBSTANCES IN PLANTS | MONSANTO TECHNOLOGY LLC (US) | 2000-07-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20010019996-A1 | PROCESS AND COMPOSITIONS PROMOTING BIOLOGICAL EFFECTIVENESS OF EXOGENOUS CHEMICAL SUBSTANCES IN PLANTS | AGXT, GLRA3, CNPY2 | DNM1 3248/4885KDM4A 1710/4885KDM4C 1125/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.