Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LIMK1 | P53667 | 2/20 | 0.41 |
| ▸ | CLK1 | P49759 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | GMNN | O75496 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.32 |
| ▸ | MMP2 | P08253 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | MMP9 | P14780 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.32 |
| ▸ | MMP8 | P22894 | 1/20 | 0.32 |
| ▸ | CCR1 | P32246 | 1/20 | 0.32 |
| ▸ | THPO | P40225 | 1/20 | 0.32 |
| ▸ | MTOR | P42345 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10054253 | 0.79 | LIMK1 (0.57) | LIMK1CLK1LMNAKDM4EGMNN | |
| SCHEMBL3965351 | 0.77 | CLK1 (0.42) | LIMK1CLK1LMNAKDM4EHSP90AA1 | |
| SCHEMBL154291 | 0.75 | GPR3 (0.52) | LIMK1KDM4EMAPTALOX15SMN1; SMN2 | |
| SCHEMBL22483140 | 0.73 | LIMK1 (0.53) | LIMK1CLK1LMNAKDM4EGMNN | |
| SCHEMBL16390728 | 0.68 | LIMK1 (0.44) | LIMK1CLK1LMNAKDM4EGMNN | |
| SCHEMBL16406208 | 0.68 | LIMK1 (0.44) | LIMK1CLK1LMNAKDM4EGMNN | |
| SCHEMBL26423615 | 0.68 | ALDH1A1 (0.42) | LIMK1CLK1LMNAKDM4EGMNN | |
| SCHEMBL24623724 | 0.67 | LIMK1 (0.46) | LIMK1CLK1LMNAKDM4EGMNN | |
| SCHEMBL17051494 | 0.66 | LIMK1 (0.49) | LIMK1CLK1LMNAKDM4EGMNN | |
| SCHEMBL149872 | 0.66 | GPR3 (0.54) | LIMK1CLK1LMNAKDM4EGMNN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1067123-A1 | NITROGENOUS HETEROCYCLIC COMPOUNDS | KYOWA HAKKO KOGYO CO., LTD. (JP) | 2001-01-10 | — | — | EP | disclosed |