Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 8/20 | 0.51 |
| ▸ | ITGAV | P06756 | 8/20 | 0.51 |
| ▸ | ITGA5 | P08648 | 4/20 | 0.51 |
| ▸ | ITGB1 | P05556 | 2/20 | 0.51 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.50 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.50 |
| ▸ | ITGB5 | P18084 | 2/20 | 0.48 |
| ▸ | SSTR1 | P30872 | 1/20 | 0.45 |
| ▸ | SSTR2 | P30874 | 1/20 | 0.45 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.45 |
| ▸ | SSTR3 | P32745 | 1/20 | 0.45 |
| ▸ | SSTR5 | P35346 | 1/20 | 0.45 |
| ▸ | MC4R | P32245 | 6/20 | 0.45 |
| ▸ | MC5R | P33032 | 6/20 | 0.45 |
| ▸ | MC3R | P41968 | 6/20 | 0.45 |
| ▸ | MC1R | Q01726 | 6/20 | 0.45 |
| ▸ | TPSAB1 | Q15661 | 3/20 | 0.44 |
| ▸ | FURIN | P09958 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8365736 | 1.00 | ITGB3 (0.51) | ITGB3ITGAVITGA5ITGB1KEAP1 | |
| SCHEMBL22738697 | 0.92 | KEAP1 (0.51) | ITGB3ITGAVITGA5ITGB1KEAP1 | |
| SCHEMBL23999261 | 0.92 | KEAP1 (0.52) | ITGB3ITGAVITGA5ITGB1KEAP1 | |
| SCHEMBL16994856 | 0.90 | ITGB3 (0.52) | ITGB3ITGAVITGA5ITGB1KEAP1 | |
| SCHEMBL15451355 | 0.90 | ITGB3 (0.52) | ITGB3ITGAVITGA5ITGB1KEAP1 | |
| SCHEMBL7738281 | 0.88 | ITGB3 (0.52) | ITGB3ITGAVITGA5ITGB1KEAP1 | |
| SCHEMBL14585795 | 0.87 | ITGB3 (0.52) | ITGB3ITGAVITGA5ITGB1KEAP1 | |
| SCHEMBL6810682 | 0.87 | ITGB3 (0.46) | ITGB3ITGAVITGA5ITGB1KEAP1 | |
| SCHEMBL7743670 | 0.86 | ITGB3 (0.56) | ITGB3ITGAVITGA5ITGB1ITGB5 | |
| SCHEMBL22970321 | 0.86 | ITGB3 (0.56) | ITGB3ITGAVITGA5ITGB1ITGB5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7179446-B2 | Simultaneous imaging of cardiac perfusion and a vitronectin receptor targeted imaging agent | BRISTOL-MYERS SQUIBB PHARMA COMPANY (US) | 2007-02-20 | — | — | US | disclosed |
| US-6537520-B1 | Diagnosis and treatment of cancer; kit containing compound having peptide or peptidomimetic functionality that binds to a alpha v beta 3 receptor linked to a chelator | BRISTOL-MYERS SQUIBB PHARMA COMPANY | 2003-03-25 | — | — | US | disclosed |