Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | QDPR | P09417 | 6/20 | 1.00 |
| ▸ | HTR1D | P28221 | 1/20 | 0.44 |
| ▸ | HTR1B | P28222 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19107630 | 0.87 | QDPR (0.77) | QDPR | |
| SCHEMBL24309677 | 0.86 | QDPR (0.75) | QDPR | |
| SCHEMBL29566914 | 0.86 | QDPR (0.75) | QDPR | |
| SCHEMBL24310465 | 0.86 | QDPR (0.75) | QDPR | |
| SCHEMBL29567164 | 0.86 | QDPR (0.75) | QDPR | |
| SCHEMBL8382547 | 0.83 | QDPR (1.00) | QDPR | |
| SCHEMBL8382616 | 0.82 | QDPR (1.00) | QDPR | |
| SCHEMBL7739767 | 0.78 | QDPR (1.00) | QDPR | |
| SCHEMBL7369176 | 0.78 | QDPR (0.72) | QDPR | |
| SCHEMBL19107631 | 0.78 | QDPR (0.64) | QDPRHTR1DHTR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5502050-A | DIHYDROXYPHENYL-SUBSTITITED PYRIDINES OR QUINONES, HYPERTENSIVE AGENTS | CORNELL RESEARCH FOUNDATION, INC. (US) | 1996-03-26 | — | — | US | claimed |
| EP-0730451-A4 | BLOCKING UTILIZATION OF TETRAHYDROBIOPTERIN TO BLOCK INDUCTION OF NITRIC OXIDE SYNTHESIS | CORNELL RES FOUNDATION INC (US) | 2001-11-28 | — | — | EP | disclosed |
| EP-0730451-A4 | BLOCKING UTILIZATION OF TETRAHYDROBIOPTERIN TO BLOCK INDUCTION OF NITRIC OXIDE SYNTHESIS | CORNELL RES FOUNDATION INC (US) | 2001-11-28 | — | — | EP | disclosed |
| US-5874433-A | Blocking utilization of tetrahydrobiopterin to block induction of nitric oxide synthesis | CORNELL RESEARCH FOUNDATION, INC. (US) | 1999-02-23 | — | — | US | disclosed |
| US-5874433-A | Blocking utilization of tetrahydrobiopterin to block induction of nitric oxide synthesis | CORNELL RESEARCH FOUNDATION, INC. (US) | 1999-02-23 | — | — | US | disclosed |
| EP-0730451-A1 | BLOCKING UTILIZATION OF TETRAHYDROBIOPTERIN TO BLOCK INDUCTION OF NITRIC OXIDE SYNTHESIS | CORNELL RESEARCH FOUNDATION, INC. (US) | 1996-09-11 | — | — | EP | disclosed |
| EP-0730451-A1 | BLOCKING UTILIZATION OF TETRAHYDROBIOPTERIN TO BLOCK INDUCTION OF NITRIC OXIDE SYNTHESIS | CORNELL RESEARCH FOUNDATION, INC. (US) | 1996-09-11 | — | — | EP | disclosed |
| US-5502050-A | DIHYDROXYPHENYL-SUBSTITITED PYRIDINES OR QUINONES, HYPERTENSIVE AGENTS | CORNELL RESEARCH FOUNDATION, INC. (US) | 1996-03-26 | — | — | US | disclosed |
| US-5502050-A | DIHYDROXYPHENYL-SUBSTITITED PYRIDINES OR QUINONES, HYPERTENSIVE AGENTS | CORNELL RESEARCH FOUNDATION, INC. (US) | 1996-03-26 | — | — | US | disclosed |
| WO-1995014468-A1 | BLOCKING UTILIZATION OF TETRAHYDROBIOPTERIN TO BLOCK INDUCTION OF NITRIC OXIDE SYNTHESIS | CORNELL RESEARCH FOUNDATION INC. (US) | 1995-06-01 | — | — | WO | disclosed |
| WO-1995014468-A1 | BLOCKING UTILIZATION OF TETRAHYDROBIOPTERIN TO BLOCK INDUCTION OF NITRIC OXIDE SYNTHESIS | CORNELL RESEARCH FOUNDATION INC. (US) | 1995-06-01 | — | — | WO | disclosed |