Pyridine

Pyridine

SCHEMBL7744539

CCCN(CCC)C(=O)[SH]CC.c1ccncc1

nearest known ligand 0.37

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TP53 P04637 1/20 0.37
CA12 O43570 1/20 0.34
CA2 P00918 1/20 0.34
CA9 Q16790 1/20 0.34
SMN1; SMN2 Q16637 2/20 0.34
L3MBTL1 Q9Y468 2/20 0.34
SLC6A2 P23975 1/20 0.33
TSHR P16473 2/20 0.32
MAPK1 P28482 1/20 0.32
ALDH1A1 P00352 3/20 0.31
LMNA P02545 1/20 0.31
GAA P10253 1/20 0.31
HTT P42858 1/20 0.31
KDM4E B2RXH2 3/20 0.31
HPGD P15428 2/20 0.31
HSD17B10 Q99714 1/20 0.31
HTR1A P08908 1/20 0.31
DRD2 P14416 1/20 0.31
HTR2A P28223 1/20 0.31
NAPRT Q6XQN6 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
S-Ethyl Dipropylcarbamothioate SCHEMBL7744541 0.72 TSHR (0.69) TP53CA12CA2CA9SMN1; SMN2
Pyridine SCHEMBL28093266 0.68 TSHR (0.47) SLC6A2TSHRKDM4EHTR1ADRD2
Pyridine SCHEMBL28812263 0.67 NAPRT (0.41) TSHRALDH1A1KDM4EHPGDNAPRT
Pyridine SCHEMBL27859626 0.66 TSHR (0.45) SLC6A2TSHRKDM4EHTR1ADRD2
Pyridine SCHEMBL4661612 0.66 FFAR3 (0.56) SMN1; SMN2TSHRALDH1A1LMNAGAA
Butyric Acid SCHEMBL5456396 0.65 FFAR3 (0.62) TSHRALDH1A1HSD17B10NAPRTTDP1
Pyridine SCHEMBL1079036 0.65 NAPRT (0.43) SMN1; SMN2L3MBTL1TSHRALDH1A1LMNA
Hexane SCHEMBL918202 0.65 TSHR (0.43) L3MBTL1TSHRALDH1A1LMNAHSD17B10
Butyric Acid SCHEMBL5874604 0.65 FFAR3 (0.62) TSHRALDH1A1HSD17B10NAPRTTDP1
Pyridine SCHEMBL242310 0.65 TDP1 (0.64) L3MBTL1TSHRALDH1A1NAPRTTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1037528-A4 AGRICULTURAL ADJUVANT COGNIS CORP (US) 2001-06-13 EP disclosed
EP-1037528-A1 AGRICULTURAL ADJUVANT Cognis Corporation (US) 2000-09-27 EP disclosed
WO-1999029171-A1 AGRICULTURAL ADJUVANT COGNIS CORPORATION (US) 1999-06-17 WO disclosed