SCHEMBL7744858

SCHEMBL7744858

CCOC(=O)C(C)C(C)=O.CCOC(=O)C(C)C(C)O

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.40
HPGD P15428 1/20 0.40
LMNA P02545 1/20 0.39
HSD17B10 Q99714 1/20 0.39
CYP2D6 P10635 1/20 0.34
CYP2C9 P11712 1/20 0.34
CYP2C19 P33261 1/20 0.34
METAP2 P50579 4/20 0.33
METAP1 P53582 4/20 0.33
ALOX15 P16050 1/20 0.33
MGAM O43451 1/20 0.33
GAA P10253 1/20 0.33
SI P14410 1/20 0.33
MGAM2 Q2M2H8 1/20 0.33
SOAT1 P35610 1/20 0.33
MEN1 O00255 1/20 0.33
NPC1 O15118 1/20 0.33
KMT2A Q03164 1/20 0.33
GLO1 Q04760 1/20 0.31
TRPA1 O75762 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31738545 0.87 ALDH1A1 (0.46) ALDH1A1HPGDLMNAHSD17B10CYP2D6
SCHEMBL2169170 0.87 ALDH1A1 (0.50) ALDH1A1HPGDLMNAHSD17B10CYP2D6
SCHEMBL41804 0.87 ALDH1A1 (0.50) ALDH1A1HPGDLMNAHSD17B10CYP2D6
SCHEMBL934321 0.87 ALDH1A1 (0.46) ALDH1A1HPGDLMNAHSD17B10CYP2D6
SCHEMBL599198 0.87 ALDH1A1 (0.46) ALDH1A1HPGDLMNAHSD17B10CYP2D6
Ethane SCHEMBL29036071 0.85 ALDH1A1 (0.48) ALDH1A1HPGDLMNAHSD17B10CYP2D6
SCHEMBL17433679 0.85 ALDH1A1 (0.48) ALDH1A1HPGDLMNAHSD17B10CYP2D6
SCHEMBL28280411 0.85 ALDH1A1 (0.48) ALDH1A1HPGDLMNAHSD17B10CYP2D6
SCHEMBL8800736 0.85 ALDH1A1 (0.48) ALDH1A1HPGDLMNAHSD17B10CYP2D6
Ammonia Solution, Strong SCHEMBL27178316 0.85 ALDH1A1 (0.43) ALDH1A1HPGDLMNAHSD17B10CYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2001013740-A1 ETHYL 3-ACETOXY-2-METHYLBUTYRATE AS A FLAVORING AGENT AND METHODS FOR PREPARING AND USING SAME BUSH BOAKE ALLEN INC. (US) 2001-03-01 WO disclosed