Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
| ▸ | FAAH | O00519 | 3/20 | 0.41 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.41 |
| ▸ | PPARG | P37231 | 4/20 | 0.40 |
| ▸ | TERT | O14746 | 3/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.40 |
| ▸ | PPARD | Q03181 | 3/20 | 0.40 |
| ▸ | PPARA | Q07869 | 3/20 | 0.40 |
| ▸ | TOP1 | P11387 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | BLM | P54132 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | FABP4 | P15090 | 2/20 | 0.40 |
| ▸ | RECQL | P46063 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | DUSP3 | P51452 | 2/20 | 0.40 |
| ▸ | GMNN | O75496 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5161538 | 1.00 | ALDH1A1 (0.57) | ALDH1A1TSHRFAAHTRPV1PPARG | |
| SCHEMBL2449791 | 0.88 | ALDH1A1 (0.47) | ALDH1A1TSHRFAAHTRPV1PPARG | |
| SCHEMBL8359629 | 0.88 | ALDH1A1 (0.47) | ALDH1A1TSHRFAAHTRPV1PPARG | |
| SCHEMBL5145224 | 0.77 | CYP1A2 (0.39) | ALDH1A1PPARGCYP1A2CYP19A1 | |
| SCHEMBL8359627 | 0.77 | ALDH1A1 (0.41) | ALDH1A1TSHRFAAHTRPV1PPARG | |
| SCHEMBL4459949 | 0.77 | ALDH1A1 (0.41) | ALDH1A1TSHRFAAHTRPV1PPARG | |
| SCHEMBL2449789 | 0.77 | ALDH1A1 (0.41) | ALDH1A1TSHRFAAHTRPV1PPARG | |
| SCHEMBL9554663 | 0.77 | ALDH1A1 (0.41) | ALDH1A1TSHRFAAHTRPV1PPARG | |
| SCHEMBL13011389 | 0.74 | ALDH1A1 (0.58) | ALDH1A1TSHRFAAHTRPV1PPARG | |
| SCHEMBL14119710 | 0.73 | ALDH1A1 (1.00) | ALDH1A1TSHRFAAHTRPV1PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6191286-B1 | REACTING AN AMINO ALKYL DIALKOXYSILANE OR AMINO TRAIALKOXYSILANE AND UNSATURATED ACID ANHYDRIDE TO FORM AN AMICACID SILANE, TREATING AMICACID SILANE WITH A SILYLATING OR ESTERIFYING CAPPING AGENT, HEATING TO FORM IMIDOSILANE | OSI SPECIALTIES INC. | 2001-02-20 | — | — | US | claimed |