SCHEMBL5145224

SCHEMBL5145224

CCCCCCCCCCCCCCCCC1CC(=O)[N]C1=O

nearest known ligand 0.39

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 3/20 0.39
ALDH1A1 P00352 2/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
CYP19A1 P11511 4/20 0.36
ALOX5 P09917 1/20 0.36
NOS1 P29475 3/20 0.35
NOS2 P35228 3/20 0.35
NOS3 P29474 2/20 0.35
GBA1 P04062 1/20 0.35
PPARG P37231 1/20 0.35
HLCS P50747 1/20 0.34
HTT P42858 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9189340 1.00 CYP1A2 (0.39) CYP1A2ALDH1A1L3MBTL1CYP19A1ALOX5
SCHEMBL6933305 1.00 CYP1A2 (0.39) CYP1A2ALDH1A1L3MBTL1CYP19A1ALOX5
SCHEMBL10437624 1.00 CYP1A2 (0.39) CYP1A2ALDH1A1L3MBTL1CYP19A1ALOX5
SCHEMBL11313115 1.00 CYP1A2 (0.39) CYP1A2ALDH1A1L3MBTL1CYP19A1ALOX5
SCHEMBL5145497 1.00 CYP1A2 (0.39) CYP1A2ALDH1A1L3MBTL1CYP19A1ALOX5
SCHEMBL6260486 0.98 CYP1A2 (0.40) CYP1A2ALDH1A1L3MBTL1CYP19A1ALOX5
SCHEMBL3265923 0.84 NOS1 (0.31) NOS1NOS2NOS3
SCHEMBL8359629 0.84 ALDH1A1 (0.47) CYP1A2ALDH1A1CYP19A1PPARG
SCHEMBL2449791 0.84 ALDH1A1 (0.47) CYP1A2ALDH1A1CYP19A1PPARG
SCHEMBL10937715 0.80 CYP1A2 (0.41) CYP1A2ALDH1A1CYP19A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7189501-B2 Silver halide color photographic photosensitive material FUJI PHOTO FILM CO., LTD. (JP) 2007-03-13 US disclosed
US-6995273-B2 1H-pyrazolo[1,5-b]-1,2,4-triazole compound, coupler and silver halide color photographic light-sensitive material FUJI PHOTO FILM CO., LTD. (JP) 2006-02-07 US disclosed
US-20050074710-A1 Silver halide color photographic photosensitive material FUJI PHOTO FILM CO., LTD. 2005-04-07 US disclosed
EP-1162504-B1 Coupler and silver halide color photographic light-sensitive material FUJI PHOTO FILM CO LTD (JP) 2004-02-18 EP disclosed
US-20040002607-A1 1H-pyrazolo[1,5-b] -1,2,4-triazole compound, coupler and silver halide color photographic light-sensitive material FUJI PHOTO FILM CO., LTD. 2004-01-01 US disclosed
US-6544724-B2 A pyrazolotriazole coupler having a specific structure including an amide linkage; improves solubility of coupler, light-fastness of dye FUJI PHOTO FILM CO., LTD. (JP) 2003-04-08 US disclosed
US-20020018973-A1 Coupler and silver halide color photographic light-sensitive material FUJI PHOTO FILM CO., LTD. 2002-02-14 US disclosed
EP-1162504-A2 Coupler and silver halide color photographic light-sensitive material FUJI PHOTO FILM CO., LTD. (JP) 2001-12-12 EP disclosed
EP-0849630-B1 Process for producing color filter FUJI PHOTO FILM CO LTD (JP) 2001-11-21 EP disclosed
EP-0849630-A2 Process for producing color filter FUJI PHOTO FILM CO., LTD. (JP) 1998-06-24 EP disclosed
EP-0571959-B1 Photographic coupler and silver halide color photographic material FUJI PHOTO FILM CO LTD (JP) 1997-04-09 EP disclosed
US-5541045-A MAGENTA COUPLERS FOR PHOTOGRAPHIC FILMS IN SILVER HALIDE EMULSIONS AND MULTILAYER ELEMENTS FUJI PHOTO FILM CO., LTD. (JP) 1996-07-30 US disclosed
US-5538842-A COLORFAST PHOTOGRAPHIC FILM FUJI PHOTO FILM CO., LTD. (JP) 1996-07-23 US disclosed
US-5532377-A MAGENTA COUPLERS FOR COLOR PHOTOGRAPHY FUJI PHOTO FILM CO., LTD. (JP) 1996-07-02 US disclosed
EP-0688774-A1 Compounds for preparing a photographic magenta coupler FUJI PHOTO FILM CO., LTD. (JP) 1995-12-27 EP disclosed
US-5451501-A Light sensitive element with magenta coupler on support FUJI PHOTO FILM CO., LTD. (JP) 1995-09-19 US disclosed
EP-0571959-A2 Photographic coupler and silver halide color photographic material FUJI PHOTO FILM CO., LTD. (JP) 1993-12-01 EP disclosed
US-4146396-A TWO EQUIVALENT COUPLER FUJI PHOTO FILM CO., LTD. (JP) 1979-03-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020018973-A1 Coupler and silver halide color photographic light-sensitive material CBR1, CBR3, GRHPR CYP1A2 915/4885ALDH1A1 289/4885L3MBTL1 1972/4885
US-20040002607-A1 1H-pyrazolo[1,5-b] -1,2,4-triazole compound, coupler and silver halide color photographic light-sensitive material CBR3, CBR1, PPOX CYP1A2 114/4885ALDH1A1 66/4885L3MBTL1 2450/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.