Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 known ✓ | P08172 | 3/20 | 0.31 |
| ▸ | CHRM1 known ✓ | P11229 | 3/20 | 0.31 |
| ▸ | CHRM3 known ✓ | P20309 | 2/20 | 0.31 |
| ▸ | CHRM5 | P08912 | 3/20 | 0.31 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL28022294 | 0.73 | CHRM2 (0.31) | CHRM2CHRM5CHRM1CHRM4CHRM3 | |
| Hydrochloric Acid SCHEMBL28201730 | 0.71 | — | — | |
| SCHEMBL13773198 | 0.65 | — | — | |
| SCHEMBL13773188 | 0.65 | — | — | |
| SCHEMBL51487 | 0.65 | — | — | |
| SCHEMBL27533253 | 0.65 | ALDH1A1 (0.38) | CHRM2CHRM5CHRM1CHRM4CHRM3 | |
| SCHEMBL25443757 | 0.63 | ALDH1A1 (0.36) | CHRM2CHRM5CHRM1CHRM4CHRM3 | |
| SCHEMBL27441234 | 0.63 | — | — | |
| Hydrochloric Acid SCHEMBL11164328 | 0.63 | — | — | |
| SCHEMBL4270564 | 0.63 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001002527-A1 | DETERGENT COMPOSITIONS OR COMPONENTS | THE PROCTER & GAMBLE COMPANY (US) | 2001-01-11 | — | — | WO | disclosed |