SCHEMBL7745010

SCHEMBL7745010

CC(C)c1cccc2c1OC(C)(C)O2

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.43
GABRA1 P14867 3/20 0.39
TSHR P16473 2/20 0.39
GABRG2 P18507 2/20 0.39
GABRB3 P28472 2/20 0.39
GABRB2 P47870 2/20 0.39
FAAH O00519 1/20 0.39
CA1 P00915 1/20 0.39
CA2 P00918 1/20 0.39
LMNA P02545 1/20 0.39
CYP1A2 P05177 1/20 0.39
CYP3A4 P08684 1/20 0.39
HPGD P15428 1/20 0.39
GABRB1 P18505 1/20 0.39
PTGS1 P23219 1/20 0.39
SLC6A2 P23975 1/20 0.39
HTR2C P28335 1/20 0.39
GABRA5 P31644 1/20 0.39
GABRA3 P34903 1/20 0.39
HTR2B P41595 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25465411 0.83 GABRA1 (0.38) GABRA1TSHRGABRG2GABRB3GABRB2
SCHEMBL15887374 0.81 GABRA1 (0.36) GABRA1TSHRGABRG2GABRB3GABRB2
SCHEMBL10122079 0.79 GABRA1 (0.38) GABRA1TSHRGABRG2GABRB3GABRB2
SCHEMBL9962275 0.79 GABRA1 (0.38) GABRA1TSHRGABRG2GABRB3GABRB2
SCHEMBL20275976 0.76 TSHR (0.37) ALDH1A1TSHRALOX15ALOX12
SCHEMBL23980767 0.74 GABRA1 (0.33) ALDH1A1GABRA1TSHRGABRG2GABRB3
SCHEMBL10522329 0.74 ALDH1A1 (0.46) ALDH1A1TSHRCA1CA2CYP1A2
SCHEMBL18970159 0.73 GABRA1 (0.44) ALDH1A1GABRA1TSHRGABRB2ALOX15
SCHEMBL29801762 0.73 GABRA1 (0.46) GABRA1TSHRGABRG2GABRB3GABRB2
SCHEMBL5503549 0.73 GABRA1 (0.46) GABRA1TSHRGABRG2GABRB3GABRB2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12024507-B2 Compounds as GLP-1R agonists TERNS PHARMACEUTICALS, INC. (US) 2024-07-02 US disclosed
CN-220989713-U Crystallization desolventizing rectifying device for liquid compound 威海市文登区检验检测中心 2024-05-24 CN disclosed
CN-117298637-A Crystallization desolventizing rectifying device for liquid compound and control method thereof 威海市文登区检验检测中心 2023-12-29 CN disclosed
EP-4269399-A1 FIVE-MEMBERED RING DERIVATIVE AND MEDICAL USE THEREOF Sichuan Haisco Pharmaceutical Co., Ltd. (CN) 2023-11-01 EP disclosed
US-20230159512-A1 COMPOUNDS AS GLP-1R AGONISTS TERNS PHARMACEUTICALS, INC. 2023-05-25 US disclosed
US-20120322761-A1 HETEROCYCLIC CETP INHIBITORS BRISTOL-MYERS SQUIBB COMPANY 2012-12-20 US disclosed
US-20120322761-A1 HETEROCYCLIC CETP INHIBITORS BRISTOL-MYERS SQUIBB COMPANY 2012-12-20 US disclosed
US-20100267669-A1 HETEROCYCLIC CETP INHIBITORS BRISTOL-MYERS SQUIBB COMPANY 2010-10-21 US disclosed
US-20100267669-A1 HETEROCYCLIC CETP INHIBITORS BRISTOL-MYERS SQUIBB COMPANY 2010-10-21 US disclosed
US-7674828-B2 Urea antagonists of P2Y1receptor useful in the treatment of thrombotic conditions BRISTOL-MYERS SQUIBB COMPANY (US) 2010-03-09 US disclosed
US-20080280905-A1 UREA ANTAGONISTS OF P2Y1 RECEPTOR USEFUL IN THE TREATMENT OF THROMBOTIC CONDITIONS BRISTOL MYERS SQUIBB COMPANY (US) 2008-11-13 US disclosed
US-20080280905-A1 UREA ANTAGONISTS OF P2Y1 RECEPTOR USEFUL IN THE TREATMENT OF THROMBOTIC CONDITIONS BRISTOL MYERS SQUIBB COMPANY (US) 2008-11-13 US disclosed
US-7388021-B2 Urea antagonists of P2Y1 receptor useful in the treatment of thrombotic conditions BRISTOL MYERS SQUIBB COMPANY (US) 2008-06-17 US disclosed
US-7388021-B2 Urea antagonists of P2Y1 receptor useful in the treatment of thrombotic conditions BRISTOL MYERS SQUIBB COMPANY (US) 2008-06-17 US disclosed
EP-0862544-B1 PROCESS FOR PURIFYING A 2,6-DIALKYLPHENOL ALBEMARLE CORP (US) 2001-01-03 EP disclosed
EP-0862544-A1 PROCESS FOR PURIFYING A 2,6-DIALKYLPHENOL ALBEMARLE CORPORATION (US) 1998-09-09 EP disclosed
US-5705039-A CONTINUOUS DISTILLATION IN OXIDATION RESISTANT ENVIRONMENT ALBEMARLE CORPORATION (US) 1998-01-06 US disclosed
US-5705039-A CONTINUOUS DISTILLATION IN OXIDATION RESISTANT ENVIRONMENT ALBEMARLE CORPORATION (US) 1998-01-06 US disclosed
WO-1997015542-A1 PROCESS FOR PURIFYING A 2,6-DIALKYLPHENOL ALBEMARLE CORPORATION (US) 1997-05-01 WO disclosed
US-5591311-A 2,6-DIISOPROPYLPHENOL ALBEMARLE CORPORATION (US) 1997-01-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080280905-A1 UREA ANTAGONISTS OF P2Y1 RECEPTOR USEFUL IN THE TREATMENT OF THROMBOTIC CONDITIONS P2RY1, P2RY11, P2RY2 ALDH1A1 1978/4885GABRA1 554/4885TSHR 1134/4885
US-12024507-B2 Compounds as GLP-1R agonists GLP1R, GIPR, GCGR ALDH1A1 3182/4885GABRA1 318/4885TSHR 80/4885
US-20230159512-A1 COMPOUNDS AS GLP-1R AGONISTS GLP1R, GIPR, GCGR ALDH1A1 3352/4885GABRA1 299/4885TSHR 82/4885
US-20120322761-A1 HETEROCYCLIC CETP INHIBITORS CETP, CES1, NPC1 ALDH1A1 2353/4885GABRA1 4260/4885TSHR 2250/4885
US-20100267669-A1 HETEROCYCLIC CETP INHIBITORS CETP, CES1, NPC1 ALDH1A1 2353/4885GABRA1 4260/4885TSHR 2250/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.