Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | CSNK2A2 | P19784 | 3/20 | 0.37 |
| ▸ | CSNK2B | P67870 | 3/20 | 0.37 |
| ▸ | CSNK2A1 | P68400 | 3/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | TET2 | Q6N021 | 1/20 | 0.33 |
| ▸ | TET1 | Q8NFU7 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.33 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.33 |
| ▸ | MATK | P42679 | 1/20 | 0.33 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.33 |
| ▸ | MAPKAPK3 | Q16644 | 1/20 | 0.33 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.33 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | CNR2 | P34972 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7745145 | 0.82 | ALDH1A1 (0.41) | KDM4EALDH1A1HPGDCSNK2A2CSNK2B | |
| SCHEMBL9569209 | 0.68 | HPGD (0.46) | KDM4EALDH1A1HPGDCSNK2A2CSNK2B | |
| SCHEMBL1007181 | 0.65 | KCNH2 (0.60) | KDM4EALDH1A1HPGDHSD17B10CYP3A4 | |
| SCHEMBL4460735 | 0.65 | KCNH2 (0.60) | KDM4EALDH1A1HPGDHSD17B10CYP3A4 | |
| SCHEMBL1629770 | 0.65 | KDM4E (0.37) | KDM4EALDH1A1HPGDCSNK2A2CSNK2B | |
| SCHEMBL9569233 | 0.65 | HPGD (0.43) | KDM4EALDH1A1HPGDCSNK2A2CSNK2B | |
| SCHEMBL9569237 | 0.65 | HPGD (0.50) | KDM4EALDH1A1HPGDCSNK2A2CSNK2B | |
| SCHEMBL9569226 | 0.64 | KDM4E (0.43) | KDM4EALDH1A1HPGDCSNK2A2CSNK2B | |
| SCHEMBL1556635 | 0.63 | ALDH1A1 (0.45) | KDM4EALDH1A1HPGDCSNK2A2CSNK2B | |
| SCHEMBL1558105 | 0.63 | ALDH1A1 (0.37) | KDM4EALDH1A1HPGDCSNK2A2CSNK2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6329391-B1 | ANTIBIOTICS, BACTERICIDES USING QUINOLONES | THE PROCTER & GAMBLE CO. | 2001-12-11 | — | — | US | claimed |