Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 8/20 | 0.42 |
| ▸ | HTR1A | P08908 | 4/20 | 0.40 |
| ▸ | DRD2 | P14416 | 2/20 | 0.40 |
| ▸ | DRD1 | P21728 | 2/20 | 0.40 |
| ▸ | DRD4 | P21917 | 2/20 | 0.40 |
| ▸ | DRD5 | P21918 | 2/20 | 0.40 |
| ▸ | DRD3 | P35462 | 2/20 | 0.40 |
| ▸ | HTR7 | P34969 | 2/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.38 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.38 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7745178 | 1.00 | MEN1 (0.46) | MEN1KMT2ASIGMAR1HTR1ADRD2 | |
| SCHEMBL7745184 | 1.00 | MEN1 (0.46) | MEN1KMT2ASIGMAR1HTR1ADRD2 | |
| SCHEMBL7413612 | 0.90 | MEN1 (0.40) | MEN1KMT2ASIGMAR1HTR1ADRD2 | |
| SCHEMBL7413619 | 0.90 | MEN1 (0.40) | MEN1KMT2ASIGMAR1HTR1ADRD2 | |
| SCHEMBL7413625 | 0.90 | MEN1 (0.40) | MEN1KMT2ASIGMAR1HTR1ADRD2 | |
| SCHEMBL7745171 | 0.84 | MEN1 (0.51) | MEN1KMT2ASIGMAR1 | |
| SCHEMBL7745176 | 0.84 | MEN1 (0.51) | MEN1KMT2ASIGMAR1 | |
| SCHEMBL7745173 | 0.84 | MEN1 (0.51) | MEN1KMT2ASIGMAR1 | |
| SCHEMBL7749731 | 0.82 | MEN1 (0.40) | MEN1KMT2ASIGMAR1HTR1ADRD2 | |
| SCHEMBL7749735 | 0.82 | MEN1 (0.40) | MEN1KMT2ASIGMAR1HTR1ADRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001032178-A1 | USE OF 3,4-SUBSTITUTED PIPERIDINES | NOVO NORDISK A/S (DK) | 2001-05-10 | — | — | WO | claimed |
| WO-2001032178-A1 | USE OF 3,4-SUBSTITUTED PIPERIDINES | NOVO NORDISK A/S (DK) | 2001-05-10 | — | — | WO | disclosed |