Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 8/20 | 0.38 |
| ▸ | NOS3 | P29474 | 1/20 | 0.38 |
| ▸ | NOS1 | P29475 | 1/20 | 0.38 |
| ▸ | NOS2 | P35228 | 1/20 | 0.38 |
| ▸ | SLC18A2 | Q05940 | 1/20 | 0.36 |
| ▸ | HTR1A | P08908 | 3/20 | 0.35 |
| ▸ | HTR7 | P34969 | 2/20 | 0.35 |
| ▸ | DRD2 | P14416 | 2/20 | 0.35 |
| ▸ | HRH2 | P25021 | 1/20 | 0.35 |
| ▸ | HRH1 | P35367 | 1/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | DRD1 | P21728 | 1/20 | 0.34 |
| ▸ | DRD4 | P21917 | 1/20 | 0.34 |
| ▸ | DRD5 | P21918 | 1/20 | 0.34 |
| ▸ | DRD3 | P35462 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7413625 | 1.00 | MEN1 (0.40) | MEN1KMT2ASIGMAR1NOS3NOS1 | |
| SCHEMBL7413619 | 1.00 | MEN1 (0.40) | MEN1KMT2ASIGMAR1NOS3NOS1 | |
| SCHEMBL7745178 | 0.90 | MEN1 (0.46) | MEN1KMT2ASIGMAR1HTR1AHTR7 | |
| SCHEMBL7745184 | 0.90 | MEN1 (0.46) | MEN1KMT2ASIGMAR1HTR1AHTR7 | |
| SCHEMBL7745181 | 0.90 | MEN1 (0.46) | MEN1KMT2ASIGMAR1HTR1AHTR7 | |
| SCHEMBL7416276 | 0.88 | SIGMAR1 (0.40) | SIGMAR1SLC18A2HTR1ADRD2DRD1 | |
| SCHEMBL8720821 | 0.88 | SIGMAR1 (0.40) | SIGMAR1SLC18A2HTR1ADRD2DRD1 | |
| Hydrochloric Acid SCHEMBL8722835 | 0.87 | SIGMAR1 (0.41) | SIGMAR1SLC18A2HTR1ADRD2DRD1 | |
| SCHEMBL7418267 | 0.84 | DRD2 (0.39) | SIGMAR1SLC18A2HTR1AHTR7DRD2 | |
| SCHEMBL7418270 | 0.84 | DRD2 (0.39) | SIGMAR1SLC18A2HTR1AHTR7DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0558487-B1 | PIPERIDINE COMPOUNDS, THEIR PREPARATION AND USE | NOVO NORDISK AS (DK) | 1998-10-07 | — | — | EP | claimed |
| EP-0558487-A1 | PIPERIDINE COMPOUNDS, THEIR PREPARATION AND USE | NOVO NORDISK A/S (DK) | 1993-09-08 | — | — | EP | claimed |
| WO-1992001672-A1 | PIPERIDINE COMPOUNDS, THEIR PREPARATION AND USE | NOVO NORDISK A/S (DK) | 1992-02-06 | — | — | WO | claimed |