Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AHR | P35869 | 2/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.44 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.44 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 2/20 | 0.43 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.43 |
| ▸ | MAOA | P21397 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | FBP1 | P09467 | 1/20 | 0.42 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11808396 | 1.00 | AHR (0.48) | AHRCYP1A2PTGS2ALOX5PTGS1 | |
| SCHEMBL8321726 | 0.80 | AHR (0.52) | AHRCYP1A2PTGS2ALOX5PTGS1 | |
| SCHEMBL5384402 | 0.78 | RELA (0.58) | PTGS2ALOX5PTGS1MAOBNFE2L2 | |
| SCHEMBL5384397 | 0.78 | RELA (0.58) | PTGS2ALOX5PTGS1MAOBNFE2L2 | |
| SCHEMBL5376234 | 0.77 | KDM4E (0.50) | PTGS2PTGS1NFE2L2 | |
| SCHEMBL5376231 | 0.77 | KDM4E (0.50) | PTGS2PTGS1NFE2L2 | |
| SCHEMBL976834 | 0.76 | APP (0.54) | CYP1A2PTGS2ALOX5PTGS1MAOB | |
| SCHEMBL7868088 | 0.76 | KDM4E (0.64) | AHRCYP1A2PTGS2ALOX5PTGS1 | |
| SCHEMBL7132075 | 0.76 | TUBB4A (0.50) | CYP1A2MAOBMAOA | |
| SCHEMBL10981021 | 0.76 | APP (0.54) | CYP1A2PTGS2ALOX5PTGS1MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6237590-B1 | Dry powder delivery system apparatus | DELSYS PHARMACEUTICAL CORPORATION | 2001-05-29 | — | — | US | disclosed |
| EP-0442180-A1 | Thermoplastic resin composition | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1991-08-21 | — | — | EP | disclosed |
| EP-0379286-A2 | Thermoplastic resin composition | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1990-07-25 | — | — | EP | disclosed |
| US-3982007-A | BENZISOTHIAZOLINONE DERIVATIVE, 2-NITROFURYL OR 2-NITROTHIENYL DERIVATIVE, ANTIMICROBIAL | SANDOZ LTD. (CH) | 1976-09-21 | — | — | US | disclosed |