Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 4/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.43 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.43 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.43 |
| ▸ | EPHX1 | P07099 | 5/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3072017 | 0.78 | ALDH1A1 (0.61) | SMN1; SMN2ALDH1A1CYP3A4TP53LMNA | |
| SCHEMBL3078929 | 0.78 | ALDH1A1 (0.61) | SMN1; SMN2ALDH1A1CYP3A4TP53LMNA | |
| SCHEMBL7745330 | 0.76 | SMN1; SMN2 (0.52) | SMN1; SMN2ALDH1A1CYP3A4TP53LMNA | |
| SCHEMBL27759933 | 0.71 | SMN1; SMN2 (0.46) | SMN1; SMN2ALDH1A1CYP3A4TP53LMNA | |
| SCHEMBL3062295 | 0.71 | ALDH1A1 (0.52) | SMN1; SMN2ALDH1A1CYP3A4TP53LMNA | |
| SCHEMBL3061955 | 0.70 | ALDH1A1 (0.50) | SMN1; SMN2ALDH1A1CYP3A4TP53LMNA | |
| SCHEMBL3082353 | 0.70 | ALDH1A1 (0.50) | SMN1; SMN2ALDH1A1CYP3A4TP53LMNA | |
| SCHEMBL14405489 | 0.70 | ALDH1A1 (0.50) | SMN1; SMN2ALDH1A1CYP3A4TP53LMNA | |
| SCHEMBL491492 | 0.69 | ALDH1A1 (1.00) | SMN1; SMN2ALDH1A1CYP3A4TP53LMNA | |
| SCHEMBL3075946 | 0.69 | ALDH1A1 (0.70) | SMN1; SMN2ALDH1A1CYP3A4TP53LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001040244-A1 | N6 HETEROCYCLIC 5' MODIFIED ADENOSINE DERIVATIVES | CV THERAPEUTICS, INC. (US) | 2001-06-07 | — | — | WO | claimed |
| WO-2001040244-A1 | N6 HETEROCYCLIC 5' MODIFIED ADENOSINE DERIVATIVES | CV THERAPEUTICS, INC. (US) | 2001-06-07 | — | — | WO | disclosed |