Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | IDO1 | P14902 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.43 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.43 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19101077 | 0.90 | IDO1 (0.53) | SMN1; SMN2CYP3A4ALDH1A1TP53IDO1 | |
| SCHEMBL6950748 | 0.90 | — | — | |
| SCHEMBL3078929 | 0.78 | ALDH1A1 (0.61) | SMN1; SMN2CYP3A4ALDH1A1TP53LMNA | |
| SCHEMBL3072017 | 0.78 | ALDH1A1 (0.61) | SMN1; SMN2CYP3A4ALDH1A1TP53LMNA | |
| SCHEMBL7745327 | 0.76 | SMN1; SMN2 (0.52) | SMN1; SMN2CYP3A4ALDH1A1TP53LMNA | |
| SCHEMBL14405489 | 0.74 | ALDH1A1 (0.50) | SMN1; SMN2CYP3A4ALDH1A1TP53LMNA | |
| SCHEMBL27540143 | 0.73 | ALDH1A1 (0.48) | SMN1; SMN2CYP3A4ALDH1A1TP53LMNA | |
| SCHEMBL6040382 | 0.72 | — | — | |
| SCHEMBL27759933 | 0.71 | SMN1; SMN2 (0.46) | SMN1; SMN2CYP3A4ALDH1A1TP53LMNA | |
| SCHEMBL3062295 | 0.71 | ALDH1A1 (0.52) | SMN1; SMN2CYP3A4ALDH1A1TP53LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001040244-A1 | N6 HETEROCYCLIC 5' MODIFIED ADENOSINE DERIVATIVES | CV THERAPEUTICS, INC. (US) | 2001-06-07 | — | — | WO | claimed |
| WO-2001040244-A1 | N6 HETEROCYCLIC 5' MODIFIED ADENOSINE DERIVATIVES | CV THERAPEUTICS, INC. (US) | 2001-06-07 | — | — | WO | disclosed |