Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 4/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MDM4 | O15151 | 1/20 | 0.36 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7747629 | 0.90 | TP53 (0.41) | TP53SMN1; SMN2LMNAMCL1MAPT | |
| SCHEMBL7740256 | 0.85 | NR3C2 (0.36) | LMNAMAPTKMT2ARAB9AMEN1 | |
| SCHEMBL7744846 | 0.83 | TP53 (0.39) | TP53SMN1; SMN2LMNAMAPTTHRB | |
| SCHEMBL7740196 | 0.77 | FSCN1 (0.34) | LMNAKMT2AALDH1A1KDM4E | |
| SCHEMBL7744815 | 0.75 | TSHR (0.34) | SMN1; SMN2LMNAKMT2AALDH1A1HPGD | |
| SCHEMBL7745253 | 0.74 | TP53 (0.37) | TP53SMN1; SMN2LMNAMAPTTHRB | |
| SCHEMBL7747648 | 0.74 | ALDH1A1 (0.35) | MAPTKMT2AALDH1A1KDM4E | |
| SCHEMBL7755890 | 0.73 | TP53 (0.36) | TP53SMN1; SMN2LMNAMAPTTHRB | |
| SCHEMBL7753781 | 0.68 | PARP10 (0.43) | TP53SMN1; SMN2LMNAMAPTTHRB | |
| SCHEMBL7745279 | 0.68 | POLB (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001009087-A1 | SUBSTITUTED ARYLHYDRAZONE CARBOXYLIC ACID DERIVATIVES AND THEIR USE AS HERBICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 2001-02-08 | — | — | WO | disclosed |