SCHEMBL7744815

SCHEMBL7744815

CCS(=O)(=O)N(C(=O)c1ccccc1)c1c[c]c(F)cc1Cl

nearest known ligand 0.34

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.34
ALDH1A1 P00352 3/20 0.33
HPGD P15428 2/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
HSD11B1 P28845 1/20 0.33
DEPTOR Q8TB45 1/20 0.33
SMN1; SMN2 Q16637 2/20 0.32
KMT2A Q03164 2/20 0.32
MEN1 O00255 1/20 0.32
POLB P06746 1/20 0.32
KDM4E B2RXH2 1/20 0.32
LMNA P02545 1/20 0.32
LIMK1 P53667 1/20 0.32
LIMK2 P53671 1/20 0.32
NR3C2 P08235 1/20 0.32
TRPM8 Q7Z2W7 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7740256 0.89 NR3C2 (0.36) TSHRHSD11B1DEPTORKMT2AMEN1
SCHEMBL7740116 0.82 FSCN1 (0.32) LMNA
SCHEMBL7747635 0.82 L3MBTL1 (0.31) TSHRALDH1A1HPGDL3MBTL1HSD11B1
SCHEMBL7745279 0.81 POLB (0.30) POLB
SCHEMBL7745401 0.75 TP53 (0.43) ALDH1A1HPGDSMN1; SMN2KMT2AMEN1
SCHEMBL7740196 0.72 FSCN1 (0.34) ALDH1A1KMT2AKDM4ELMNA
SCHEMBL7744842 0.71 NR3C2 (0.34) ALDH1A1HPGDHSD11B1KMT2AMEN1
SCHEMBL7753474 0.71 NR3C2 (0.33) HSD11B1NR3C2TRPM8
SCHEMBL7745253 0.70 TP53 (0.37) ALDH1A1SMN1; SMN2KMT2APOLBLMNA
SCHEMBL7755890 0.70 TP53 (0.36) ALDH1A1HPGDSMN1; SMN2KMT2APOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2001009087-A1 SUBSTITUTED ARYLHYDRAZONE CARBOXYLIC ACID DERIVATIVES AND THEIR USE AS HERBICIDES BAYER AKTIENGESELLSCHAFT (DE) 2001-02-08 WO disclosed