Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1B1 | P15121 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7740409 | 0.93 | MEN1 (0.42) | AKR1B1CYP1A2CYP2C19USP2SMN1; SMN2 | |
| SCHEMBL7745019 | 0.82 | KDM4E (0.47) | AKR1B1SMN1; SMN2KMT2AKDM4EL3MBTL1 | |
| SCHEMBL7745460 | 0.81 | TSHR (0.61) | AKR1B1USP2SMN1; SMN2MEN1KMT2A | |
| SCHEMBL7740405 | 0.81 | KDM4E (0.43) | AKR1B1USP2MEN1KMT2AKDM4E | |
| SCHEMBL7745467 | 0.81 | TOP2A (0.49) | AKR1B1CYP1A2USP2MEN1KMT2A | |
| SCHEMBL7745824 | 0.81 | MEN1 (0.40) | AKR1B1CYP1A2CYP2C19USP2MEN1 | |
| SCHEMBL7745216 | 0.81 | TSHR (0.50) | AKR1B1USP2SMN1; SMN2MEN1KMT2A | |
| SCHEMBL5858779 | 0.80 | SLC9A1 (0.46) | CYP1A2CYP2C19USP2SMN1; SMN2MEN1 | |
| SCHEMBL8365513 | 0.77 | TP53 (0.45) | USP2SMN1; SMN2MEN1KMT2AKDM4E | |
| SCHEMBL7747798 | 0.77 | MEN1 (0.41) | AKR1B1USP2SMN1; SMN2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6774134-B2 | FOR THERAPY OF RESPIRATORY SYNCYTIAL VIRUS INFECTION | BRISTOL-MYERS SQUIBB COMPANY | 2004-08-10 | — | — | US | disclosed |
| US-6774134-B2 | FOR THERAPY OF RESPIRATORY SYNCYTIAL VIRUS INFECTION | BRISTOL-MYERS SQUIBB COMPANY | 2004-08-10 | — | — | US | disclosed |