Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN11 | Q06124 | 6/20 | 0.48 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.40 |
| ▸ | RARB | P10826 | 4/20 | 0.40 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.40 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.40 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.40 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.40 |
| ▸ | PRKAG3 | Q9UGI9 | 1/20 | 0.40 |
| ▸ | PRKAG2 | Q9UGJ0 | 1/20 | 0.40 |
| ▸ | PRKAB1 | Q9Y478 | 1/20 | 0.40 |
| ▸ | PTGES | O14684 | 1/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.40 |
| ▸ | RARA | P10276 | 1/20 | 0.39 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9189121 | 0.84 | PTPN11 (0.53) | PTPN11MCL1RARBRARA | |
| SCHEMBL7750426 | 0.84 | LMNA (0.42) | RARBPTGES | |
| SCHEMBL7750435 | 0.84 | LMNA (0.42) | RARBPTGES | |
| SCHEMBL7750487 | 0.84 | LMNA (0.42) | RARBPTGES | |
| SCHEMBL7750480 | 0.84 | LMNA (0.42) | RARBPTGES | |
| SCHEMBL28709974 | 0.82 | PTPN11 (0.51) | PTPN11MCL1RARBRARA | |
| SCHEMBL7745535 | 0.79 | NPC1 (0.50) | — | |
| SCHEMBL8625748 | 0.79 | NPC1 (0.50) | — | |
| SCHEMBL9120381 | 0.79 | RARB (0.46) | RARB | |
| SCHEMBL9121323 | 0.79 | RARB (0.46) | RARB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0821049-B1 | Cyclopentyl compounds | ROLIC AG (CH) | 2001-01-10 | — | — | EP | disclosed |
| EP-0821049-A1 | Cyclopentyl compounds | Rolic AG (CH) | 1998-01-28 | — | — | EP | disclosed |