Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | PTGS1 | P23219 | 8/20 | 0.48 |
| ▸ | PTGS2 | P35354 | 7/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | EEF2K | O00418 | 1/20 | 0.45 |
| ▸ | SRC | P12931 | 1/20 | 0.45 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8962055 | 0.81 | GAA (0.49) | GAAPTGS1PTGS2MEN1ALDH1A1 | |
| SCHEMBL8962112 | 0.74 | PTGS1 (0.56) | GAAPTGS1PTGS2MEN1ALDH1A1 | |
| SCHEMBL8962003 | 0.74 | PTGS1 (0.56) | GAAPTGS1PTGS2MEN1ALDH1A1 | |
| SCHEMBL8961998 | 0.74 | PTGS1 (0.56) | GAAPTGS1PTGS2MEN1ALDH1A1 | |
| SCHEMBL7702588 | 0.67 | GAA (1.00) | GAAPTGS1PTGS2MEN1ALDH1A1 | |
| SCHEMBL7702586 | 0.67 | GAA (1.00) | GAAPTGS1PTGS2MEN1ALDH1A1 | |
| SCHEMBL7193575 | 0.65 | PTGS2 (0.70) | GAAPTGS1PTGS2MEN1ALDH1A1 | |
| SCHEMBL7697041 | 0.65 | PTGS2 (1.00) | GAAPTGS1PTGS2MEN1ALDH1A1 | |
| SCHEMBL7697044 | 0.65 | PTGS2 (1.00) | GAAPTGS1PTGS2MEN1ALDH1A1 | |
| SCHEMBL9371718 | 0.65 | PTGS2 (0.66) | GAAPTGS1PTGS2MEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001021166-A1 | TREATMENT AND PREVENTION OF HEPATIC DISORDERS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2001-03-29 | — | — | WO | disclosed |
| US-5494927-A | INHIBITS ACTIVITY OF 5-LIPOXYGENASE AND-OR CYCLOOXYGENASE | WARNER-LAMBERT COMPANY (US) | 1996-02-27 | — | — | US | disclosed |