Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.64 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.64 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.60 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | TP53 | P04637 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7740562 | 0.87 | TSHR (0.57) | TSHRMAPK1NPSR1MAPTSMN1; SMN2 | |
| SCHEMBL7745839 | 0.83 | TSHR (0.52) | TSHRMAPK1NPSR1PTK2BMAPT | |
| SCHEMBL7745373 | 0.81 | MAPK1 (0.50) | TSHRMAPK1NPSR1MAPTSMN1; SMN2 | |
| SCHEMBL7741297 | 0.81 | TSHR (0.50) | TSHRMAPK1NPSR1PTK2BMAPT | |
| SCHEMBL18539751 | 0.80 | SMN1; SMN2 (0.57) | TSHRMAPK1NPSR1PTK2BMAPT | |
| SCHEMBL7740571 | 0.79 | TSHR (0.56) | TSHRMAPK1MAPTSMN1; SMN2TP53 | |
| Hydrochloric Acid SCHEMBL5858859 | 0.79 | TSHR (0.70) | TSHRMAPK1MAPTSMN1; SMN2TP53 | |
| SCHEMBL7745214 | 0.79 | TSHR (0.47) | TSHRMAPK1NPSR1PTK2BMAPT | |
| SCHEMBL7741104 | 0.78 | TSHR (0.55) | TSHRMAPK1NPSR1MAPTSMN1; SMN2 | |
| SCHEMBL14733928 | 0.78 | TSHR (1.00) | TSHRMAPK1MAPTSMN1; SMN2TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6774134-B2 | FOR THERAPY OF RESPIRATORY SYNCYTIAL VIRUS INFECTION | BRISTOL-MYERS SQUIBB COMPANY | 2004-08-10 | — | — | US | disclosed |
| US-6774134-B2 | FOR THERAPY OF RESPIRATORY SYNCYTIAL VIRUS INFECTION | BRISTOL-MYERS SQUIBB COMPANY | 2004-08-10 | — | — | US | disclosed |