Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.57 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | CES1 | P23141 | 3/20 | 0.45 |
| ▸ | BCHE | P06276 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | ALDH2 | P05091 | 2/20 | 0.44 |
| ▸ | ALDH3A1 | P30838 | 2/20 | 0.44 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | TGM2 | P21980 | 2/20 | 0.43 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7745697 | 0.87 | TSHR (0.64) | TSHRMAPK1NPSR1ALDH1A1TP53 | |
| SCHEMBL7745839 | 0.86 | TSHR (0.52) | TSHRMAPK1NPSR1ALDH1A1TP53 | |
| SCHEMBL7745373 | 0.85 | MAPK1 (0.50) | TSHRMAPK1NPSR1ALDH1A1TP53 | |
| SCHEMBL7741297 | 0.85 | TSHR (0.50) | TSHRMAPK1NPSR1ALDH1A1TP53 | |
| SCHEMBL7745462 | 0.84 | POLB (0.46) | CES1BCHEALDH1A1ALDH2ALDH3A1 | |
| SCHEMBL7740965 | 0.83 | TSHR (0.49) | TSHRCES1BCHEALDH1A1ALDH2 | |
| SCHEMBL7745214 | 0.82 | TSHR (0.47) | TSHRMAPK1NPSR1TP53POLB | |
| SCHEMBL6480793 | 0.82 | CES1 (0.45) | TSHRCES1BCHEALDH1A1ALDH2 | |
| SCHEMBL7745174 | 0.82 | MAPK1 (0.47) | TSHRMAPK1NPSR1ALDH1A1TP53 | |
| SCHEMBL7745732 | 0.81 | TSHR (0.46) | TSHRMAPK1NPSR1BCHEALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6774134-B2 | FOR THERAPY OF RESPIRATORY SYNCYTIAL VIRUS INFECTION | BRISTOL-MYERS SQUIBB COMPANY | 2004-08-10 | — | — | US | disclosed |
| US-6774134-B2 | FOR THERAPY OF RESPIRATORY SYNCYTIAL VIRUS INFECTION | BRISTOL-MYERS SQUIBB COMPANY | 2004-08-10 | — | — | US | disclosed |