Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.57 |
| ▸ | GAA | P10253 | 3/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.57 |
| ▸ | TSHR | P16473 | 2/20 | 0.57 |
| ▸ | USP2 | O75604 | 2/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 2/20 | 0.55 |
| ▸ | GLA | P06280 | 1/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 3/20 | 0.55 |
| ▸ | PKM | P14618 | 2/20 | 0.55 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.52 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 5/20 | 0.50 |
| ▸ | RAB9A | P51151 | 5/20 | 0.50 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23530752 | 0.82 | NPSR1 (0.47) | SMN1; SMN2GAAALDH1A1TSHRUSP2 | |
| SCHEMBL7745697 | 0.80 | TSHR (0.64) | SMN1; SMN2GAAALDH1A1TSHRUSP2 | |
| SCHEMBL243922 | 0.75 | LMNA (0.61) | SMN1; SMN2GAAUSP2KDM4EMAPT | |
| SCHEMBL1059693 | 0.75 | RAB9A (0.64) | SMN1; SMN2GAAUSP2KDM4EMAPT | |
| SCHEMBL5156990 | 0.74 | GRM2 (0.81) | SMN1; SMN2GAAALDH1A1KDM4EMAPT | |
| SCHEMBL757031 | 0.73 | RAB9A (0.62) | SMN1; SMN2GAAALDH1A1TSHRUSP2 | |
| SCHEMBL30037937 | 0.73 | RAB9A (0.62) | SMN1; SMN2GAAALDH1A1TSHRUSP2 | |
| SCHEMBL9569938 | 0.72 | HDAC6 (0.67) | SMN1; SMN2GAAALDH1A1TSHRUSP2 | |
| SCHEMBL3874703 | 0.72 | RAB9A (0.57) | SMN1; SMN2GAAUSP2KDM4EMAPT | |
| SCHEMBL14374007 | 0.72 | GRM2 (0.72) | SMN1; SMN2GAAALDH1A1KDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170050992-A1 | NOVEL ANNELATED PHENOXYACETAMIDES | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2017-02-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170050992-A1 | NOVEL ANNELATED PHENOXYACETAMIDES | EP300, NAT1, AADAC | SMN1; SMN2 3829/4885GAA 2793/4885ALDH1A1 144/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.