Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 3/20 | 0.37 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 6/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | TP53 | P04637 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7745478 | 0.88 | GRM2 (0.41) | ALDH1A1KDM4ETSHRPTK2BMAPT | |
| SCHEMBL8366756 | 0.87 | ALDH1A1 (0.38) | ALDH1A1KDM4ETSHRPTK2BMAPT | |
| SCHEMBL7745967 | 0.87 | ALDH1A1 (0.39) | ALDH1A1KDM4ETSHRPTK2BMAPT | |
| SCHEMBL7745578 | 0.85 | TSHR (0.41) | ALDH1A1KDM4ETSHRPTK2BMAPT | |
| SCHEMBL7745784 | 0.78 | CYP3A4 (0.40) | ALDH1A1KDM4ETSHRPTK2BMAPT | |
| SCHEMBL7746108 | 0.77 | TSHR (0.33) | ALDH1A1KDM4ETSHRPTK2BMAPT | |
| SCHEMBL7745936 | 0.75 | TSHR (0.41) | ALDH1A1TSHRPTK2BMAPTPOLB | |
| SCHEMBL7748043 | 0.75 | CYP3A4 (0.42) | ALDH1A1KDM4ETSHRPTK2BMAPT | |
| SCHEMBL7745732 | 0.74 | TSHR (0.46) | ALDH1A1TSHRMAPTPOLBLMNA | |
| SCHEMBL7746299 | 0.74 | TSHR (0.40) | ALDH1A1KDM4ETSHRPTK2BMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6774134-B2 | FOR THERAPY OF RESPIRATORY SYNCYTIAL VIRUS INFECTION | BRISTOL-MYERS SQUIBB COMPANY | 2004-08-10 | — | — | US | disclosed |