Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | TSHR | P16473 | 4/20 | 0.35 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 4/20 | 0.34 |
| ▸ | TP53 | P04637 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.33 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7746108 | 0.89 | TSHR (0.33) | ALDH1A1KDM4EMAPTTSHRPTK2B | |
| SCHEMBL7745970 | 0.87 | ALDH1A1 (0.39) | ALDH1A1KDM4EMAPTTSHRPTK2B | |
| SCHEMBL7745478 | 0.87 | GRM2 (0.41) | ALDH1A1KDM4EMAPTTSHRPTK2B | |
| SCHEMBL8363973 | 0.86 | ALDH1A1 (0.38) | ALDH1A1KDM4EMAPTTSHRPTK2B | |
| SCHEMBL8363907 | 0.84 | ALDH1A1 (0.43) | ALDH1A1KDM4EMAPTTSHRPTK2B | |
| SCHEMBL7745971 | 0.78 | TP53 (0.34) | ALDH1A1MAPTTSHRPTK2BLMNA | |
| SCHEMBL7745784 | 0.77 | CYP3A4 (0.40) | ALDH1A1KDM4EMAPTTSHRPTK2B | |
| SCHEMBL7746216 | 0.76 | MAPT (0.38) | ALDH1A1MAPTTSHRPTK2BLMNA | |
| SCHEMBL7746066 | 0.75 | TP53 (0.37) | ALDH1A1MAPTTSHRLMNATP53 | |
| SCHEMBL7745967 | 0.74 | ALDH1A1 (0.39) | ALDH1A1KDM4EMAPTTSHRPTK2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6774134-B2 | FOR THERAPY OF RESPIRATORY SYNCYTIAL VIRUS INFECTION | BRISTOL-MYERS SQUIBB COMPANY | 2004-08-10 | — | — | US | disclosed |