Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.34 |
| ▸ | KDM4A | O75164 | 1/20 | 0.34 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.34 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.34 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7746036 | 0.90 | LMNA (0.32) | LMNA | |
| SCHEMBL7746021 | 0.86 | ALDH1A1 (0.39) | LMNAMEN1KMT2A | |
| SCHEMBL24681420 | 0.86 | ALDH1A1 (0.39) | LMNAMEN1KMT2A | |
| SCHEMBL26022372 | 0.86 | ALDH1A1 (0.39) | LMNAMEN1KMT2A | |
| SCHEMBL9191489 | 0.85 | LMNA (0.43) | LMNAKDM4CKDM4APHF8KDM2A | |
| SCHEMBL8222274 | 0.85 | — | — | |
| SCHEMBL8208557 | 0.85 | — | — | |
| SCHEMBL7743439 | 0.82 | ACE2 (0.44) | LMNAMEN1KMT2A | |
| SCHEMBL11398471 | 0.82 | LMNA (0.50) | LMNAPTPN1MEN1CYP3A4ALOX15 | |
| SCHEMBL8218646 | 0.82 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001002512-A1 | USE OF DIMERIZED FISCHER-TROPSCH PROCESS PRODUCTS AND VINYLIDENE DERIVATIVES THEREOF | SASOL TECHNOLOGY (PTY) LTD. (ZA) | 2001-01-11 | — | — | WO | disclosed |