Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.44 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.40 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | FAAH | O00519 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7743439 | 1.00 | ACE2 (0.44) | ACE2FFAR4FFAR1SPHK1LMNA | |
| SCHEMBL7743511 | 0.96 | ACE2 (0.40) | ACE2LMNAALDH1A1TSHRMEN1 | |
| SCHEMBL7746021 | 0.92 | ALDH1A1 (0.39) | LMNAALDH1A1TSHRMEN1FAAH | |
| SCHEMBL26022372 | 0.92 | ALDH1A1 (0.39) | LMNAALDH1A1TSHRMEN1FAAH | |
| SCHEMBL24681420 | 0.92 | ALDH1A1 (0.39) | LMNAALDH1A1TSHRMEN1FAAH | |
| SCHEMBL23923682 | 0.90 | ACE2 (0.50) | ACE2FFAR4FFAR1SPHK1LMNA | |
| SCHEMBL7746036 | 0.88 | LMNA (0.32) | ACE2LMNA | |
| SCHEMBL27795701 | 0.86 | ACE2 (0.43) | ACE2FFAR4FFAR1SPHK1LMNA | |
| SCHEMBL7744198 | 0.86 | ACE2 (0.46) | ACE2FFAR4FFAR1SPHK1LMNA | |
| SCHEMBL7738197 | 0.86 | ACE2 (0.46) | ACE2FFAR4FFAR1SPHK1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001002512-A1 | USE OF DIMERIZED FISCHER-TROPSCH PROCESS PRODUCTS AND VINYLIDENE DERIVATIVES THEREOF | SASOL TECHNOLOGY (PTY) LTD. (ZA) | 2001-01-11 | — | — | WO | disclosed |