Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 4/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7741428 | 0.84 | TSHR (0.52) | MEN1KMT2AUSP2L3MBTL1POLB | |
| SCHEMBL7746306 | 0.82 | MEN1 (0.42) | MEN1KMT2AUSP2L3MBTL1POLB | |
| SCHEMBL6481692 | 0.81 | KMT2A (0.45) | MEN1KMT2AUSP2L3MBTL1POLB | |
| SCHEMBL7746349 | 0.81 | L3MBTL1 (0.41) | MEN1KMT2AUSP2L3MBTL1POLB | |
| SCHEMBL7745593 | 0.81 | CYP3A4 (0.43) | MEN1KMT2AUSP2L3MBTL1POLB | |
| SCHEMBL7741873 | 0.80 | MEN1 (0.41) | MEN1KMT2AUSP2L3MBTL1POLB | |
| SCHEMBL7741461 | 0.80 | TSHR (0.48) | MEN1KMT2AUSP2L3MBTL1POLB | |
| SCHEMBL15587601 | 0.78 | CYP3A4 (0.41) | MEN1KMT2AUSP2L3MBTL1POLB | |
| SCHEMBL6480793 | 0.76 | CES1 (0.45) | MEN1KMT2AUSP2L3MBTL1TSHR | |
| SCHEMBL7745584 | 0.72 | TSHR (0.42) | MEN1KMT2AUSP2L3MBTL1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6774134-B2 | FOR THERAPY OF RESPIRATORY SYNCYTIAL VIRUS INFECTION | BRISTOL-MYERS SQUIBB COMPANY | 2004-08-10 | — | — | US | disclosed |
| US-6774134-B2 | FOR THERAPY OF RESPIRATORY SYNCYTIAL VIRUS INFECTION | BRISTOL-MYERS SQUIBB COMPANY | 2004-08-10 | — | — | US | disclosed |