Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7746316 | 0.84 | MEN1 (0.42) | TSHRTP53POLBMAPTSMN1; SMN2 | |
| SCHEMBL7740571 | 0.81 | TSHR (0.56) | TSHRMAPK1TP53POLBMAPT | |
| SCHEMBL7746872 | 0.80 | TSHR (0.54) | TSHRMAPK1TP53POLBMAPT | |
| SCHEMBL7745697 | 0.76 | TSHR (0.64) | TSHRMAPK1TP53POLBMAPT | |
| SCHEMBL7740562 | 0.76 | TSHR (0.57) | TSHRMAPK1TP53POLBMAPT | |
| SCHEMBL3727049 | 0.76 | TSHR (0.54) | TSHRMAPK1TP53POLBMAPT | |
| SCHEMBL16163238 | 0.75 | TSHR (0.53) | TSHRMAPK1 | |
| SCHEMBL3738360 | 0.75 | TSHR (0.53) | TSHRMAPK1TP53POLBMAPT | |
| SCHEMBL7741104 | 0.74 | TSHR (0.55) | TSHRMAPK1TP53POLBMAPT | |
| SCHEMBL16163229 | 0.73 | TSHR (0.51) | TSHRMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6774134-B2 | FOR THERAPY OF RESPIRATORY SYNCYTIAL VIRUS INFECTION | BRISTOL-MYERS SQUIBB COMPANY | 2004-08-10 | — | — | US | disclosed |
| US-6774134-B2 | FOR THERAPY OF RESPIRATORY SYNCYTIAL VIRUS INFECTION | BRISTOL-MYERS SQUIBB COMPANY | 2004-08-10 | — | — | US | disclosed |